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Airway epithelial repair: breathtakingly quick and multipotentially pathogenic

Erjefält, Jonas LU and Persson, Carl LU (1997) In Thorax 52(11). p.1010-1012
Abstract
Epithelial shedding, even to the point of airway denudation, had already been described as a common and unifying feature of asthma by the latter half of the 19th century. However, the repair processes that specifically follow the shedding-like loss of epithelial cells have only recently been examined in vivo. This paper discusses the exceedingly fast epithelial restitution and the potential pathogenic sequelae to epithelial shedding alone that have been unravelled. Epithelial cytoprotection emerges as an important property of future therapeutic drugs for the treatment of airways inflammatory conditions.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
asthma pathology, mucosal barrier, epithelial repair
in
Thorax
volume
52
issue
11
pages
1010 - 1012
publisher
BMJ Publishing Group
external identifiers
  • pmid:9487352
  • scopus:0030778321
ISSN
1468-3296
language
English
LU publication?
yes
id
bd2df619-1f95-4b9f-a7e0-9057dd398d40 (old id 1112489)
alternative location
http://thorax.bmj.com/cgi/reprint/52/11/1010
date added to LUP
2008-07-22 12:24:28
date last changed
2017-06-11 04:31:36
@article{bd2df619-1f95-4b9f-a7e0-9057dd398d40,
  abstract     = {Epithelial shedding, even to the point of airway denudation, had already been described as a common and unifying feature of asthma by the latter half of the 19th century. However, the repair processes that specifically follow the shedding-like loss of epithelial cells have only recently been examined in vivo. This paper discusses the exceedingly fast epithelial restitution and the potential pathogenic sequelae to epithelial shedding alone that have been unravelled. Epithelial cytoprotection emerges as an important property of future therapeutic drugs for the treatment of airways inflammatory conditions.},
  author       = {Erjefält, Jonas and Persson, Carl},
  issn         = {1468-3296},
  keyword      = {asthma pathology,mucosal barrier,epithelial repair},
  language     = {eng},
  number       = {11},
  pages        = {1010--1012},
  publisher    = {BMJ Publishing Group},
  series       = {Thorax},
  title        = {Airway epithelial repair: breathtakingly quick and multipotentially pathogenic},
  volume       = {52},
  year         = {1997},
}