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Adrenoleukodystrophy--unusual CT and MR findings in two siblings. Case reports

Sundgren, P C ; Blennow, Gösta LU ; Englund, Elisabet LU and Holtås, Stig LU (1998) In Acta Radiologica 39(1). p.77-80
Abstract
PURPOSE: To describe the unusual appearance of adrenoleukodystrophy (ALD) in MR imaging. MATERIAL AND METHODS: An analysis was made of MR findings, histopathology and clinical course in the cases of two brothers with ALD. RESULTS: The older brother presented with frontal contrast-enhanced lesions, including a cyst. These were initially misinterpreted as a tumour at both radiology and pathology. The correct diagnosis was made after the discovery of very-long-chain fatty acids in the blood. The younger brother presented initially with involvement of various segments of the corticospinal tract. CONCLUSION: It is important that the radiologist be aware of the variants of ALD in MR imaging so as to avoid diagnostic mistakes.
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Radiologica
volume
39
issue
1
pages
77 - 80
publisher
SAGE Publications
external identifiers
  • pmid:9498875
ISSN
1600-0455
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Paediatrics (Lund) (013002000), Pathology, (Lund) (013030000), Diagnostic Radiology, (Lund) (013038000)
id
4eb5b832-afee-4403-b16d-5e7b2e0915a5 (old id 1113236)
date added to LUP
2016-04-01 16:58:17
date last changed
2018-11-21 20:45:35
@article{4eb5b832-afee-4403-b16d-5e7b2e0915a5,
  abstract     = {PURPOSE: To describe the unusual appearance of adrenoleukodystrophy (ALD) in MR imaging. MATERIAL AND METHODS: An analysis was made of MR findings, histopathology and clinical course in the cases of two brothers with ALD. RESULTS: The older brother presented with frontal contrast-enhanced lesions, including a cyst. These were initially misinterpreted as a tumour at both radiology and pathology. The correct diagnosis was made after the discovery of very-long-chain fatty acids in the blood. The younger brother presented initially with involvement of various segments of the corticospinal tract. CONCLUSION: It is important that the radiologist be aware of the variants of ALD in MR imaging so as to avoid diagnostic mistakes.},
  author       = {Sundgren, P C and Blennow, Gösta and Englund, Elisabet and Holtås, Stig},
  issn         = {1600-0455},
  language     = {eng},
  number       = {1},
  pages        = {77--80},
  publisher    = {SAGE Publications},
  series       = {Acta Radiologica},
  title        = {Adrenoleukodystrophy--unusual CT and MR findings in two siblings. Case reports},
  volume       = {39},
  year         = {1998},
}