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Wilms' tumour in infancy

Kullendorff, Carl-Magnus LU and Wiebe, Thomas LU (1998) In Acta Pædiatrica 87(7). p.747-750
Abstract
During a 15-y period, 48 children were treated for Wilms' tumour (WT). Seven of them were < 1 y of age at diagnosis. One child presented with non-traumatic haematuria, but in all the other children WT was revealed as a palpable abdominal mass at routine examination or investigation due to another disease. The four children under 6 months of age at diagnosis were primarily operated upon; the others received preoperative chemotherapy. Two children had chromosomal aberrations in the WT tumour specimen. The follow-up revealed that postoperatively six children are healthy with no evidence of relapse from WT, but one child had a contralateral relapse successfully enucleated. The clinical behaviour and management of WT in infants differ... (More)
During a 15-y period, 48 children were treated for Wilms' tumour (WT). Seven of them were < 1 y of age at diagnosis. One child presented with non-traumatic haematuria, but in all the other children WT was revealed as a palpable abdominal mass at routine examination or investigation due to another disease. The four children under 6 months of age at diagnosis were primarily operated upon; the others received preoperative chemotherapy. Two children had chromosomal aberrations in the WT tumour specimen. The follow-up revealed that postoperatively six children are healthy with no evidence of relapse from WT, but one child had a contralateral relapse successfully enucleated. The clinical behaviour and management of WT in infants differ compared with that in older children. The diagnosis may be uncertain and it can be difficult to distinguish between malignant and non-malignant lesions. It is essential to realize the possibility of WT, even in children < 1 y of age. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Pædiatrica
volume
87
issue
7
pages
747 - 750
publisher
Taylor & Francis
external identifiers
  • pmid:9722247
  • scopus:0031843477
ISSN
1651-2227
language
English
LU publication?
yes
id
60083186-3e51-44d4-867b-dfb22126d728 (old id 1113467)
alternative location
http://www.ingentaconnect.com/content/apl/spae/1998/00000087/00000007/art00009
date added to LUP
2008-07-15 10:31:21
date last changed
2017-01-01 07:23:22
@article{60083186-3e51-44d4-867b-dfb22126d728,
  abstract     = {During a 15-y period, 48 children were treated for Wilms' tumour (WT). Seven of them were &lt; 1 y of age at diagnosis. One child presented with non-traumatic haematuria, but in all the other children WT was revealed as a palpable abdominal mass at routine examination or investigation due to another disease. The four children under 6 months of age at diagnosis were primarily operated upon; the others received preoperative chemotherapy. Two children had chromosomal aberrations in the WT tumour specimen. The follow-up revealed that postoperatively six children are healthy with no evidence of relapse from WT, but one child had a contralateral relapse successfully enucleated. The clinical behaviour and management of WT in infants differ compared with that in older children. The diagnosis may be uncertain and it can be difficult to distinguish between malignant and non-malignant lesions. It is essential to realize the possibility of WT, even in children &lt; 1 y of age.},
  author       = {Kullendorff, Carl-Magnus and Wiebe, Thomas},
  issn         = {1651-2227},
  language     = {eng},
  number       = {7},
  pages        = {747--750},
  publisher    = {Taylor & Francis},
  series       = {Acta Pædiatrica},
  title        = {Wilms' tumour in infancy},
  volume       = {87},
  year         = {1998},
}