Reproducibility of ultrasonic fetal volume blood flow measurements
(1998) In Clinical Physiology 18(5). p.479-485- Abstract
- The intraobserver reproducibility of ultrasonic volume blood flow measurements in the human fetus was evaluated in this study. A new approach, simultaneous measurement of the vessel diameter and the flow velocity with a pulsed-wave Doppler ultrasound synchronized with a real-time ultrasound phase-locked echo-tracking system, was used to estimate volume blood flow (VBF) in the fetal descending aorta. Measurements were performed in a longitudinal study on 20 normally grown fetuses. Intraobserver reproducibility of repeated estimations of mean blood flow velocities throughout gestation was very good, with high values of intraclass correlation coefficient (IntraCC 0.80-0.91) and low values of coefficient of variation (CV 4-11%). The IntraCC of... (More)
- The intraobserver reproducibility of ultrasonic volume blood flow measurements in the human fetus was evaluated in this study. A new approach, simultaneous measurement of the vessel diameter and the flow velocity with a pulsed-wave Doppler ultrasound synchronized with a real-time ultrasound phase-locked echo-tracking system, was used to estimate volume blood flow (VBF) in the fetal descending aorta. Measurements were performed in a longitudinal study on 20 normally grown fetuses. Intraobserver reproducibility of repeated estimations of mean blood flow velocities throughout gestation was very good, with high values of intraclass correlation coefficient (IntraCC 0.80-0.91) and low values of coefficient of variation (CV 4-11%). The IntraCC of repeated vessel diameter measurements throughout gestation was low (0.30-0.68), whereas the values of CV were acceptable (< 12%), with the exception of the period between 140 and 167 gestational days (CV > 12%). The lower reproducibility of vessel diameter measurement contributed directly to the relatively low reproducibility of VBF estimations overall (IntraCC 0.25-0.70; CV 17-28%), as these are calculated from a formula using both flow velocity and vessel diameter. Nevertheless, the synchronized approach gives absolute values of vessel diameter, flow velocity and VBF comparable with values reported in the human fetus previously. The new method provides, by taking the vessel wall pulsations into consideration and by measuring diameter and velocity simultaneously, a more complete information on fetal haemodynamics and fetal physiology. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1113833
- author
- Brodszki, Jana LU ; Gardiner, H M ; Eriksson, A ; Stale, Håkan LU and Marsal, Karel LU
- organization
- publishing date
- 1998
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Doppler ultrasound, fetal blood flow, intraobserver agreement, ultrasound, velocity, vessel diameter
- in
- Clinical Physiology
- volume
- 18
- issue
- 5
- pages
- 479 - 485
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- pmid:9784945
- scopus:0031682208
- ISSN
- 1365-2281
- DOI
- 10.1046/j.1365-2281.1998.00127.x
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Obstetrics and Gynaecology (Lund) (013018000), Biomedical Engineering (011200011), Pediatrics/Urology/Gynecology/Endocrinology (013240400)
- id
- 09c5cec7-18de-49b4-b4c6-03e2727e67bd (old id 1113833)
- date added to LUP
- 2016-04-01 11:53:20
- date last changed
- 2022-01-26 19:42:48
@article{09c5cec7-18de-49b4-b4c6-03e2727e67bd,
abstract = {{The intraobserver reproducibility of ultrasonic volume blood flow measurements in the human fetus was evaluated in this study. A new approach, simultaneous measurement of the vessel diameter and the flow velocity with a pulsed-wave Doppler ultrasound synchronized with a real-time ultrasound phase-locked echo-tracking system, was used to estimate volume blood flow (VBF) in the fetal descending aorta. Measurements were performed in a longitudinal study on 20 normally grown fetuses. Intraobserver reproducibility of repeated estimations of mean blood flow velocities throughout gestation was very good, with high values of intraclass correlation coefficient (IntraCC 0.80-0.91) and low values of coefficient of variation (CV 4-11%). The IntraCC of repeated vessel diameter measurements throughout gestation was low (0.30-0.68), whereas the values of CV were acceptable (< 12%), with the exception of the period between 140 and 167 gestational days (CV > 12%). The lower reproducibility of vessel diameter measurement contributed directly to the relatively low reproducibility of VBF estimations overall (IntraCC 0.25-0.70; CV 17-28%), as these are calculated from a formula using both flow velocity and vessel diameter. Nevertheless, the synchronized approach gives absolute values of vessel diameter, flow velocity and VBF comparable with values reported in the human fetus previously. The new method provides, by taking the vessel wall pulsations into consideration and by measuring diameter and velocity simultaneously, a more complete information on fetal haemodynamics and fetal physiology.}},
author = {{Brodszki, Jana and Gardiner, H M and Eriksson, A and Stale, Håkan and Marsal, Karel}},
issn = {{1365-2281}},
keywords = {{Doppler ultrasound; fetal blood flow; intraobserver agreement; ultrasound; velocity; vessel diameter}},
language = {{eng}},
number = {{5}},
pages = {{479--485}},
publisher = {{John Wiley & Sons Inc.}},
series = {{Clinical Physiology}},
title = {{Reproducibility of ultrasonic fetal volume blood flow measurements}},
url = {{http://dx.doi.org/10.1046/j.1365-2281.1998.00127.x}},
doi = {{10.1046/j.1365-2281.1998.00127.x}},
volume = {{18}},
year = {{1998}},
}