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Salmeterol and physical performance at -15 degrees C in highly trained nonasthmatic cross-country skiers

Sue-Chu, M; Sandsund, M; Helgerud, J; Reinertsen, R E and Bjermer, Leif LU (1999) In Scandinavian Journal of Medicine & Science in Sports 9(1). p.48-52
Abstract
The aim of this double-blind, placebo-controlled, cross-over study was to investigate possible improvement in physical performance at an ambient temperature of -15 degrees C by an inhaled dose of 50 micrograms salmeterol in 8 highly trained nonasthmatic cross-country skiers. FEV1 was measured before, during and after the treadmill exercise protocol, which consisted of a warm-up run, runs of 10 min at 90% and 5 min at 80% VO2max, followed by a timed run to exhaustion. Despite a significant improvement in FEV1, salmeterol did not have a beneficial effect on heart rate, blood lactate concentration, respiratory exchange ratio, oxygen uptake or minute ventilation during the exercise protocol. Running time to exhaustion was not significantly... (More)
The aim of this double-blind, placebo-controlled, cross-over study was to investigate possible improvement in physical performance at an ambient temperature of -15 degrees C by an inhaled dose of 50 micrograms salmeterol in 8 highly trained nonasthmatic cross-country skiers. FEV1 was measured before, during and after the treadmill exercise protocol, which consisted of a warm-up run, runs of 10 min at 90% and 5 min at 80% VO2max, followed by a timed run to exhaustion. Despite a significant improvement in FEV1, salmeterol did not have a beneficial effect on heart rate, blood lactate concentration, respiratory exchange ratio, oxygen uptake or minute ventilation during the exercise protocol. Running time to exhaustion was not significantly different from placebo. This lack of enhancement of exercise performance in healthy endurance athletes further supports the recent approval of salmeterol for prophylactic use by asthmatic athletes during training and competition. (Less)
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author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
salmeterol, physical performance, skiing, athletes
in
Scandinavian Journal of Medicine & Science in Sports
volume
9
issue
1
pages
48 - 52
publisher
Wiley-Blackwell
external identifiers
  • pmid:9974197
  • scopus:0033073405
ISSN
1600-0838
DOI
10.1111/j.1600-0838.1999.tb00206.x
language
English
LU publication?
no
id
09eb222f-be92-4e64-8f54-ed7e886d3012 (old id 1114393)
date added to LUP
2008-07-04 09:28:22
date last changed
2017-09-10 04:41:20
@article{09eb222f-be92-4e64-8f54-ed7e886d3012,
  abstract     = {The aim of this double-blind, placebo-controlled, cross-over study was to investigate possible improvement in physical performance at an ambient temperature of -15 degrees C by an inhaled dose of 50 micrograms salmeterol in 8 highly trained nonasthmatic cross-country skiers. FEV1 was measured before, during and after the treadmill exercise protocol, which consisted of a warm-up run, runs of 10 min at 90% and 5 min at 80% VO2max, followed by a timed run to exhaustion. Despite a significant improvement in FEV1, salmeterol did not have a beneficial effect on heart rate, blood lactate concentration, respiratory exchange ratio, oxygen uptake or minute ventilation during the exercise protocol. Running time to exhaustion was not significantly different from placebo. This lack of enhancement of exercise performance in healthy endurance athletes further supports the recent approval of salmeterol for prophylactic use by asthmatic athletes during training and competition.},
  author       = {Sue-Chu, M and Sandsund, M and Helgerud, J and Reinertsen, R E and Bjermer, Leif},
  issn         = {1600-0838},
  keyword      = {salmeterol,physical performance,skiing,athletes},
  language     = {eng},
  number       = {1},
  pages        = {48--52},
  publisher    = {Wiley-Blackwell},
  series       = {Scandinavian Journal of Medicine & Science in Sports},
  title        = {Salmeterol and physical performance at -15 degrees C in highly trained nonasthmatic cross-country skiers},
  url          = {http://dx.doi.org/10.1111/j.1600-0838.1999.tb00206.x},
  volume       = {9},
  year         = {1999},
}