Advanced

Five homologous repeats of the protein G-related protein MIG cooperate in binding to goat immunoglobulin G

Vasi, J; Svensson, J; Frick, Inga-Maria LU and Muller, H P (1999) In Infection and Immunity 67(1). p.413-416
Abstract
Protein MIG, from Streptococcus dysgalactiae, binds alpha2-macroglobulin and immunoglobulin G (IgG). MIG-derived fusion proteins with one to five IgG-binding repeats differed up to 72,000- fold in avidity for goat IgG, indicating a considerable cooperativity of the repeats. Significant sequence variation in the IgG-binding repeats was recognized. Protein MIG interacted with goat IgG1 via both the Fc and Fab parts.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Infection and Immunity
volume
67
issue
1
pages
413 - 416
publisher
American Society for Microbiology
external identifiers
  • pmid:9864244
  • scopus:0032918534
ISSN
1098-5522
language
English
LU publication?
yes
id
040dc67f-993a-4005-ab3b-7626ef762628 (old id 1114651)
alternative location
http://iai.highwire.org/cgi/content/full/67/1/413
date added to LUP
2008-07-04 14:40:44
date last changed
2017-01-01 04:48:52
@article{040dc67f-993a-4005-ab3b-7626ef762628,
  abstract     = {Protein MIG, from Streptococcus dysgalactiae, binds alpha2-macroglobulin and immunoglobulin G (IgG). MIG-derived fusion proteins with one to five IgG-binding repeats differed up to 72,000- fold in avidity for goat IgG, indicating a considerable cooperativity of the repeats. Significant sequence variation in the IgG-binding repeats was recognized. Protein MIG interacted with goat IgG1 via both the Fc and Fab parts.},
  author       = {Vasi, J and Svensson, J and Frick, Inga-Maria and Muller, H P},
  issn         = {1098-5522},
  language     = {eng},
  number       = {1},
  pages        = {413--416},
  publisher    = {American Society for Microbiology},
  series       = {Infection and Immunity},
  title        = {Five homologous repeats of the protein G-related protein MIG cooperate in binding to goat immunoglobulin G},
  volume       = {67},
  year         = {1999},
}