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Radiation dosimetry in nuclear medicine

Stabin, M G ; Tagesson, Magnus ; Thomas, S R ; Ljungberg, Michael LU and Strand, Sven-Erik LU (1999) In Applied Radiation and Isotopes 50(1). p.73-87
Abstract
Radionuclides are used in nuclear medicine in a variety of diagnostic and therapeutic procedures. A knowledge of the radiation dose received by different organs in the body is essential to an evaluation of the risks and benefits of any procedure. In this paper, current methods for internal dosimetry are reviewed, as they are applied in nuclear medicine. Particularly, the Medical Internal Radiation Dose (MIRD) system for dosimetry is explained, and many of its published resources discussed. Available models representing individuals of different age and gender, including those representing the pregnant woman are described; current trends in establishing models for individual patients are also evaluated. The proper design of kinetic studies... (More)
Radionuclides are used in nuclear medicine in a variety of diagnostic and therapeutic procedures. A knowledge of the radiation dose received by different organs in the body is essential to an evaluation of the risks and benefits of any procedure. In this paper, current methods for internal dosimetry are reviewed, as they are applied in nuclear medicine. Particularly, the Medical Internal Radiation Dose (MIRD) system for dosimetry is explained, and many of its published resources discussed. Available models representing individuals of different age and gender, including those representing the pregnant woman are described; current trends in establishing models for individual patients are also evaluated. The proper design of kinetic studies for establishing radiation doses for radiopharmaceuticals is discussed. An overview of how to use information obtained in a dosimetry study, including that of the effective dose equivalent (ICRP 30) and effective dose (ICRP 60), is given. Current trends and issues in internal dosimetry, including the calculation of patient-specific doses and in the use of small scale and microdosimetry techniques, are also reviewed. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
dosimetry, radiation dose, thallium 201, single photon emission computer tomography, thallium 204, iodine 125, polonium
in
Applied Radiation and Isotopes
volume
50
issue
1
pages
73 - 87
publisher
Elsevier
external identifiers
  • pmid:10028629
  • scopus:0032916189
ISSN
0969-8043
DOI
10.1016/S0969-8043(98)00023-2
language
English
LU publication?
yes
id
a6614b1d-23e5-4707-bbbc-8728ace34b16 (old id 1115063)
date added to LUP
2016-04-01 12:27:04
date last changed
2022-03-29 01:02:43
@article{a6614b1d-23e5-4707-bbbc-8728ace34b16,
  abstract     = {{Radionuclides are used in nuclear medicine in a variety of diagnostic and therapeutic procedures. A knowledge of the radiation dose received by different organs in the body is essential to an evaluation of the risks and benefits of any procedure. In this paper, current methods for internal dosimetry are reviewed, as they are applied in nuclear medicine. Particularly, the Medical Internal Radiation Dose (MIRD) system for dosimetry is explained, and many of its published resources discussed. Available models representing individuals of different age and gender, including those representing the pregnant woman are described; current trends in establishing models for individual patients are also evaluated. The proper design of kinetic studies for establishing radiation doses for radiopharmaceuticals is discussed. An overview of how to use information obtained in a dosimetry study, including that of the effective dose equivalent (ICRP 30) and effective dose (ICRP 60), is given. Current trends and issues in internal dosimetry, including the calculation of patient-specific doses and in the use of small scale and microdosimetry techniques, are also reviewed.}},
  author       = {{Stabin, M G and Tagesson, Magnus and Thomas, S R and Ljungberg, Michael and Strand, Sven-Erik}},
  issn         = {{0969-8043}},
  keywords     = {{dosimetry; radiation dose; thallium 201; single photon emission computer tomography; thallium 204; iodine 125; polonium}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{73--87}},
  publisher    = {{Elsevier}},
  series       = {{Applied Radiation and Isotopes}},
  title        = {{Radiation dosimetry in nuclear medicine}},
  url          = {{http://dx.doi.org/10.1016/S0969-8043(98)00023-2}},
  doi          = {{10.1016/S0969-8043(98)00023-2}},
  volume       = {{50}},
  year         = {{1999}},
}