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Is the lack of concurrence of bacterial vaginosis and vaginal candidosis explained by the presence of bacterial amines?

Rodrigues, A G; Mårdh, Per-Anders LU ; Pina-Vaz, C; Martinez-de-Oliveira, J and da Fonseca, A F (1999) In American Journal of Obstetrics and Gynecology 181(2). p.367-370
Abstract
OBJECTIVE AND STUDY DESIGN: We report for the first time an inhibitory effect on cell division and germ tube formation by Candida albicans and strains of other Candida species by putrescine and cadaverine. RESULTS: Both bacterial amines showed a dose-dependent inhibition of germ tube formation by C albicans, as well as budding (inhibition of cell division) of strains of other Candida species (ie, C glabrata, C krusei, and C tropicalis). CONCLUSIONS: We hypothesize that the presence of these and possibly other bacterial amines produced by anaerobes in the vaginal flora and seen in bacterial vaginosis, as in the healthy gut, may explain why candidosis is rarely seen in these instances.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Candida albicans, Vaginitis, Bacteriosis, Candidiasis, Putrescine, Cadaverine, Inhibitor, Germination, Concomitant disease, Vaginal fluid, Pathogenesis, Human, Female, Infection, Mycosis, Fungi Imperfecti, Fungi, Thallophyta, Female genital diseases, Vaginal diseases, Amine
in
American Journal of Obstetrics and Gynecology
volume
181
issue
2
pages
367 - 370
publisher
Elsevier
external identifiers
  • pmid:10454684
  • scopus:0032869742
ISSN
1097-6868
language
English
LU publication?
yes
id
6dc2abf3-25bc-4fd3-8fa5-b4384b4fb5ce (old id 1115856)
date added to LUP
2008-07-08 15:05:14
date last changed
2017-08-13 03:32:12
@article{6dc2abf3-25bc-4fd3-8fa5-b4384b4fb5ce,
  abstract     = {OBJECTIVE AND STUDY DESIGN: We report for the first time an inhibitory effect on cell division and germ tube formation by Candida albicans and strains of other Candida species by putrescine and cadaverine. RESULTS: Both bacterial amines showed a dose-dependent inhibition of germ tube formation by C albicans, as well as budding (inhibition of cell division) of strains of other Candida species (ie, C glabrata, C krusei, and C tropicalis). CONCLUSIONS: We hypothesize that the presence of these and possibly other bacterial amines produced by anaerobes in the vaginal flora and seen in bacterial vaginosis, as in the healthy gut, may explain why candidosis is rarely seen in these instances.},
  author       = {Rodrigues, A G and Mårdh, Per-Anders and Pina-Vaz, C and Martinez-de-Oliveira, J and da Fonseca, A F},
  issn         = {1097-6868},
  keyword      = {Candida albicans,Vaginitis,Bacteriosis,Candidiasis,Putrescine,Cadaverine,Inhibitor,Germination,Concomitant disease,Vaginal fluid,Pathogenesis,Human,Female,Infection,Mycosis,Fungi Imperfecti,Fungi,Thallophyta,Female genital diseases,Vaginal diseases,Amine},
  language     = {eng},
  number       = {2},
  pages        = {367--370},
  publisher    = {Elsevier},
  series       = {American Journal of Obstetrics and Gynecology},
  title        = {Is the lack of concurrence of bacterial vaginosis and vaginal candidosis explained by the presence of bacterial amines?},
  volume       = {181},
  year         = {1999},
}