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Photocoagulation of diabetic macular oedema--complications and visual outcome

Lövestam Adrian, Monica LU and Agardh, Elisabet LU (2000) In Acta Ophthalmologica Scandinavica 78(6). p.667-671
Abstract
PURPOSE: To describe complications and visual outcome of photocoagulation for clinically significant macular oedema. SUBJECTS AND METHODS: Evaluation of macular oedema and complications of photocoagulation in 194 eyes, defined as subretinal fibrosis, atrophic creep of the pigment epithelium and subretinal neovascularization was based on stereo fundus photo grading. The study included 25 patients with type 1 and 93 patients with type 2 diabetes (age 32 +/- 10 and 65 +/- 9 years, respectively). The statistical evaluations were based on one eye per patient. RESULTS: Follow-up time was 5.5 +/- 2.4 years (mean +/- SD). Complications within 1/3 ODD from the centre of the macula were seen in 4% (1/23) of eyes of patients with type 1 diabetes,... (More)
PURPOSE: To describe complications and visual outcome of photocoagulation for clinically significant macular oedema. SUBJECTS AND METHODS: Evaluation of macular oedema and complications of photocoagulation in 194 eyes, defined as subretinal fibrosis, atrophic creep of the pigment epithelium and subretinal neovascularization was based on stereo fundus photo grading. The study included 25 patients with type 1 and 93 patients with type 2 diabetes (age 32 +/- 10 and 65 +/- 9 years, respectively). The statistical evaluations were based on one eye per patient. RESULTS: Follow-up time was 5.5 +/- 2.4 years (mean +/- SD). Complications within 1/3 ODD from the centre of the macula were seen in 4% (1/23) of eyes of patients with type 1 diabetes, compared to 26% (20/76) of eyes among patients with type 2 diabetes (p=0.02). Hard exsudates before treatment were more common in type 2 than in type 1 diabetic eyes, 70/82 vs. 11/23 (p<0.001). In all eyes, hard exsudates were more often associated with subretinal fibrosis or atrophic creep (35/133 eyes) than diffuse oedema (5/44 eyes) (p=0.04). CONCLUSION: Photocoagulation for clinically significant macular oedema with hard exudates, particularly when subfoveally located, was more often associated with subretinal fibrosis or atrophic creep of the pigment epithelium than photocoagulation of oedema without hard exudates. Hard exudates as well as complications after photocoagulation were more common in type 2 than in type 1 diabetes, resulting in poorer visual outcome in this group of patients. (Less)
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author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
diabetes, oedema, hard exudates, photocoagulation, atrophic creep, fibrosis
in
Acta Ophthalmologica Scandinavica
volume
78
issue
6
pages
667 - 671
publisher
Wiley
external identifiers
  • pmid:11167229
  • scopus:0033665796
ISSN
1395-3907
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Unit on Vascular Diabetic Complications (013241510), Ophthalmology (Lund) (013043000)
id
ac561add-dc33-4b19-856f-504dadd2be94 (old id 1116183)
alternative location
http://www.ingentaconnect.com/content/mksg/aos/2000/00000078/00000006/art00013
date added to LUP
2016-04-01 16:43:13
date last changed
2022-01-28 21:39:29
@article{ac561add-dc33-4b19-856f-504dadd2be94,
  abstract     = {{PURPOSE: To describe complications and visual outcome of photocoagulation for clinically significant macular oedema. SUBJECTS AND METHODS: Evaluation of macular oedema and complications of photocoagulation in 194 eyes, defined as subretinal fibrosis, atrophic creep of the pigment epithelium and subretinal neovascularization was based on stereo fundus photo grading. The study included 25 patients with type 1 and 93 patients with type 2 diabetes (age 32 +/- 10 and 65 +/- 9 years, respectively). The statistical evaluations were based on one eye per patient. RESULTS: Follow-up time was 5.5 +/- 2.4 years (mean +/- SD). Complications within 1/3 ODD from the centre of the macula were seen in 4% (1/23) of eyes of patients with type 1 diabetes, compared to 26% (20/76) of eyes among patients with type 2 diabetes (p=0.02). Hard exsudates before treatment were more common in type 2 than in type 1 diabetic eyes, 70/82 vs. 11/23 (p&lt;0.001). In all eyes, hard exsudates were more often associated with subretinal fibrosis or atrophic creep (35/133 eyes) than diffuse oedema (5/44 eyes) (p=0.04). CONCLUSION: Photocoagulation for clinically significant macular oedema with hard exudates, particularly when subfoveally located, was more often associated with subretinal fibrosis or atrophic creep of the pigment epithelium than photocoagulation of oedema without hard exudates. Hard exudates as well as complications after photocoagulation were more common in type 2 than in type 1 diabetes, resulting in poorer visual outcome in this group of patients.}},
  author       = {{Lövestam Adrian, Monica and Agardh, Elisabet}},
  issn         = {{1395-3907}},
  keywords     = {{diabetes; oedema; hard exudates; photocoagulation; atrophic creep; fibrosis}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{667--671}},
  publisher    = {{Wiley}},
  series       = {{Acta Ophthalmologica Scandinavica}},
  title        = {{Photocoagulation of diabetic macular oedema--complications and visual outcome}},
  url          = {{http://www.ingentaconnect.com/content/mksg/aos/2000/00000078/00000006/art00013}},
  volume       = {{78}},
  year         = {{2000}},
}