The prognosis for type 2 diabetic patients with heart disease. A 10-year observation study of 385 patients
(2000) In Journal of Diabetes and its Complications 14(6). p.301-306- Abstract
- The objective was to study the development and progression of heart disease in type 2 diabetic patients and to evaluate the influence of revascularisation procedures on its outcome. A 10-year observation study in 385 patients attending a hospital-based outpatient clinic was performed. A total of 156/385 patients developed myocardial infarction (n=68), angina (n=44), heart failure (n=34) or died (n=109). A high mortality was seen in patients with myocardial infarction (73%) and heart failure (71%), in contrast, to patients with angina (25%). Thirty patients had a coronary angiography because of angina, out of which 23 were revascularised. Four (17%) of patients with bypass surgery or angioplasty died compared with 57 (67%) of the patients... (More)
- The objective was to study the development and progression of heart disease in type 2 diabetic patients and to evaluate the influence of revascularisation procedures on its outcome. A 10-year observation study in 385 patients attending a hospital-based outpatient clinic was performed. A total of 156/385 patients developed myocardial infarction (n=68), angina (n=44), heart failure (n=34) or died (n=109). A high mortality was seen in patients with myocardial infarction (73%) and heart failure (71%), in contrast, to patients with angina (25%). Thirty patients had a coronary angiography because of angina, out of which 23 were revascularised. Four (17%) of patients with bypass surgery or angioplasty died compared with 57 (67%) of the patients with no intervention (p<0.001). The occurrence of myocardial infarction was associated with age (p<0.0001), and mean systolic (p<0.05) and diastolic (p<0.05) blood pressure and degree of albuminuria at entry (p<0.05). Heart failure was associated with age (p<0.0001), and mean HbA(1c) levels (p<0.05), while angina was associated with age only (p<0.05). Death was associated with age (p<0.0001), diabetes duration (p<0.05), mean diastolic blood pressure (p<0.05), and degree of albuminuria at entry (p<0.0001). This study shows a high incidence of heart disease in patients with type 2 diabetes. The prognosis was better in patients who had had a revascularisation procedure. Thus, a more active attitude towards revascularisation may potentially improve the prognosis for type 2 diabetic patients with atherosclerotic heart disease. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1116194
- author
- Torffvit, Ole LU and Agardh, Carl-David LU
- organization
- publishing date
- 2000
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Angina pectoris, Myocardial infarction, Heart failure, Angioplasty, Bypass surgery, Type 2 diabetes mellitus
- in
- Journal of Diabetes and its Complications
- volume
- 14
- issue
- 6
- pages
- 301 - 306
- publisher
- Elsevier
- external identifiers
-
- pmid:11120453
- scopus:0033673728
- ISSN
- 1873-460X
- DOI
- 10.1016/S1056-8727(00)00117-3
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Medicine (Lund) (013230025), Unit on Vascular Diabetic Complications (013241510)
- id
- 78d67889-d48c-481d-b643-fa0c88716c16 (old id 1116194)
- date added to LUP
- 2016-04-01 16:47:44
- date last changed
- 2024-01-11 14:53:48
@article{78d67889-d48c-481d-b643-fa0c88716c16,
abstract = {{The objective was to study the development and progression of heart disease in type 2 diabetic patients and to evaluate the influence of revascularisation procedures on its outcome. A 10-year observation study in 385 patients attending a hospital-based outpatient clinic was performed. A total of 156/385 patients developed myocardial infarction (n=68), angina (n=44), heart failure (n=34) or died (n=109). A high mortality was seen in patients with myocardial infarction (73%) and heart failure (71%), in contrast, to patients with angina (25%). Thirty patients had a coronary angiography because of angina, out of which 23 were revascularised. Four (17%) of patients with bypass surgery or angioplasty died compared with 57 (67%) of the patients with no intervention (p<0.001). The occurrence of myocardial infarction was associated with age (p<0.0001), and mean systolic (p<0.05) and diastolic (p<0.05) blood pressure and degree of albuminuria at entry (p<0.05). Heart failure was associated with age (p<0.0001), and mean HbA(1c) levels (p<0.05), while angina was associated with age only (p<0.05). Death was associated with age (p<0.0001), diabetes duration (p<0.05), mean diastolic blood pressure (p<0.05), and degree of albuminuria at entry (p<0.0001). This study shows a high incidence of heart disease in patients with type 2 diabetes. The prognosis was better in patients who had had a revascularisation procedure. Thus, a more active attitude towards revascularisation may potentially improve the prognosis for type 2 diabetic patients with atherosclerotic heart disease.}},
author = {{Torffvit, Ole and Agardh, Carl-David}},
issn = {{1873-460X}},
keywords = {{Angina pectoris; Myocardial infarction; Heart failure; Angioplasty; Bypass surgery; Type 2 diabetes mellitus}},
language = {{eng}},
number = {{6}},
pages = {{301--306}},
publisher = {{Elsevier}},
series = {{Journal of Diabetes and its Complications}},
title = {{The prognosis for type 2 diabetic patients with heart disease. A 10-year observation study of 385 patients}},
url = {{http://dx.doi.org/10.1016/S1056-8727(00)00117-3}},
doi = {{10.1016/S1056-8727(00)00117-3}},
volume = {{14}},
year = {{2000}},
}