Advanced

Preoperative ropivacaine infiltration in breast surgery

Johansson, Arne LU ; Axelson, Jan LU ; Ingvar, Christian LU ; Luttropp, Hans-Henrik LU and Lundberg, Johan LU (2000) In Acta Anaesthesiologica Scandinavica 44(9). p.1093-1098
Abstract
Purpose:



The aim of the study was to investigate whether preoperative infiltration with ropivacaine in conjunction with breast surgery improves postoperative pain management and attenuates postoperative nausea and vomiting.

Method:



Prospective, randomised, double-blind study, including 60 healthy women (ASA 1–2) allocated to one of two groups. Thirty patients were given 0.3 ml/kg saline in the operating field before surgery. Another 30 patients received a similar volume of ropivacaine 3.75 mg/ml. A visual analogue scale (0–100 mm) was used for evaluation of postoperative pain, nausea and vomiting. If the score was more than 30 mm at rest, the patients were given ketobemidone i.v. as treatment... (More)
Purpose:



The aim of the study was to investigate whether preoperative infiltration with ropivacaine in conjunction with breast surgery improves postoperative pain management and attenuates postoperative nausea and vomiting.

Method:



Prospective, randomised, double-blind study, including 60 healthy women (ASA 1–2) allocated to one of two groups. Thirty patients were given 0.3 ml/kg saline in the operating field before surgery. Another 30 patients received a similar volume of ropivacaine 3.75 mg/ml. A visual analogue scale (0–100 mm) was used for evaluation of postoperative pain, nausea and vomiting. If the score was more than 30 mm at rest, the patients were given ketobemidone i.v. as treatment for postoperative pain, and dixyrazine i.v. against nausea and vomiting. The intra- and postoperative analgesic requirements and postoperative nausea and vomiting were registered.



Results: The intraoperative fentanyl consumption was similar in the saline group 81±22 μg vs 76±28 μg; (ns) in the ropivacaine group. The postoperative 24-h ketobemidone consumption was also similar to those treated with ropivacaine (4.2±2.6 mg vs 4.2±4.3 mg; ns). Postoperative nausea and vomiting (PONV) occurred with similar frequencies in both groups. The 24-h dixyrazine consumption was the same in the two groups (2.1±2.7 mg in the saline group compared to 2.4±2.8 mg in the ropivacaine group; ns). After 6 h recovery, 41% of all patients had experienced nausea and 20% vomiting.



Conclusion: We found no differences in postoperative pain management between 3.75 mg/ml ropivacaine and saline wound infiltration before breast surgery. The data show similar postoperative needs of analgesics and antiemetics with a similar frequency of PONV. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Anaesthesiologica Scandinavica
volume
44
issue
9
pages
1093 - 1098
publisher
Wiley-Blackwell
external identifiers
  • scopus:0033802858
ISSN
0001-5172
DOI
10.1034/j.1399-6576.2000.440910.x
language
English
LU publication?
yes
id
d586915a-4110-4a68-ac0c-0702efcd231f (old id 1117705)
alternative location
http://onlinelibrary.wiley.com/doi/10.1034/j.1399-6576.2000.440910.x/full
http://www.ncbi.nlm.nih.gov/pubmed/11028729
date added to LUP
2008-06-26 15:46:20
date last changed
2017-06-18 03:41:51
@article{d586915a-4110-4a68-ac0c-0702efcd231f,
  abstract     = {Purpose:<br/><br>
<br/><br>
The aim of the study was to investigate whether preoperative infiltration with ropivacaine in conjunction with breast surgery improves postoperative pain management and attenuates postoperative nausea and vomiting.<br/><br>
Method:<br/><br>
<br/><br>
Prospective, randomised, double-blind study, including 60 healthy women (ASA 1–2) allocated to one of two groups. Thirty patients were given 0.3 ml/kg saline in the operating field before surgery. Another 30 patients received a similar volume of ropivacaine 3.75 mg/ml. A visual analogue scale (0–100 mm) was used for evaluation of postoperative pain, nausea and vomiting. If the score was more than 30 mm at rest, the patients were given ketobemidone i.v. as treatment for postoperative pain, and dixyrazine i.v. against nausea and vomiting. The intra- and postoperative analgesic requirements and postoperative nausea and vomiting were registered.<br/><br>
<br/><br>
Results: The intraoperative fentanyl consumption was similar in the saline group 81±22 μg vs 76±28 μg; (ns) in the ropivacaine group. The postoperative 24-h ketobemidone consumption was also similar to those treated with ropivacaine (4.2±2.6 mg vs 4.2±4.3 mg; ns). Postoperative nausea and vomiting (PONV) occurred with similar frequencies in both groups. The 24-h dixyrazine consumption was the same in the two groups (2.1±2.7 mg in the saline group compared to 2.4±2.8 mg in the ropivacaine group; ns). After 6 h recovery, 41% of all patients had experienced nausea and 20% vomiting.<br/><br>
<br/><br>
Conclusion: We found no differences in postoperative pain management between 3.75 mg/ml ropivacaine and saline wound infiltration before breast surgery. The data show similar postoperative needs of analgesics and antiemetics with a similar frequency of PONV.},
  author       = {Johansson, Arne and Axelson, Jan and Ingvar, Christian and Luttropp, Hans-Henrik and Lundberg, Johan},
  issn         = {0001-5172},
  language     = {eng},
  number       = {9},
  pages        = {1093--1098},
  publisher    = {Wiley-Blackwell},
  series       = {Acta Anaesthesiologica Scandinavica},
  title        = {Preoperative ropivacaine infiltration in breast surgery},
  url          = {http://dx.doi.org/10.1034/j.1399-6576.2000.440910.x},
  volume       = {44},
  year         = {2000},
}