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Oxytocin receptor mimetics prepared by molecular imprinting.

Kempe, Maria LU (2000) In Letters in Peptide Science 7(1). p.27-33
Abstract
Oxytocin receptor mimetics were prepared by molecular imprinting using Z-oxytocin as the template. Comparative binding studies with reference polymers showed that the imprinted polymers recognized both Z-oxytocin and unprotected oxytocin selectively. The dissociation constants were 47 µM and 102 µM,respectively, and the density of binding sites was 12 µmol/g. The synthetic oxytocin receptors were easily prepared, possessed high mechanical and chemical stability, and were reused without loss of selectivity and capacity after regeneration by extraction.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Letters in Peptide Science
volume
7
issue
1
pages
27 - 33
publisher
Springer
external identifiers
  • scopus:0033980120
ISSN
0929-5666
DOI
10.1023/A:1008919213207
language
English
LU publication?
yes
id
ee618935-f110-45fb-b4e0-1b1abb34497b (old id 1118160)
date added to LUP
2008-06-19 13:16:37
date last changed
2017-01-01 07:03:35
@article{ee618935-f110-45fb-b4e0-1b1abb34497b,
  abstract     = {Oxytocin receptor mimetics were prepared by molecular imprinting using Z-oxytocin as the template. Comparative binding studies with reference polymers showed that the imprinted polymers recognized both Z-oxytocin and unprotected oxytocin selectively. The dissociation constants were 47 µM and 102 µM,respectively, and the density of binding sites was 12 µmol/g. The synthetic oxytocin receptors were easily prepared, possessed high mechanical and chemical stability, and were reused without loss of selectivity and capacity after regeneration by extraction.},
  author       = {Kempe, Maria},
  issn         = {0929-5666},
  language     = {eng},
  number       = {1},
  pages        = {27--33},
  publisher    = {Springer},
  series       = {Letters in Peptide Science},
  title        = {Oxytocin receptor mimetics prepared by molecular imprinting.},
  url          = {http://dx.doi.org/10.1023/A:1008919213207},
  volume       = {7},
  year         = {2000},
}