Assessment of environmental tobacco smoke exposure in children with asthmatic symptoms by questionnaire and cotinine concentrations in plasma, saliva, and urine
(2000) In Journal of Clinical Epidemiology 53(7). p.715-721- Abstract
- To validate a detailed questionnaire for assessment of environmental tobacco smoke (ETS) exposure by the biomarker cotinine in various media, a population-based study in the urban area of Malmo, Sweden was performed in children aged 8-13 years with and without asthmatic symptoms. There were strong correlations between urinary and saliva cotinine concentrations and also, though to a lesser extent, between these media and plasma. Even a detailed questionnaire gave only a rough picture of the ETS exposure, as indicated by the biomarkers. In a multivariate model, the most significant questionnaire-derived predictor of the cotinine levels was the maternal smoking habits; other questionnaire variables gave only a minimal explained variance.... (More)
- To validate a detailed questionnaire for assessment of environmental tobacco smoke (ETS) exposure by the biomarker cotinine in various media, a population-based study in the urban area of Malmo, Sweden was performed in children aged 8-13 years with and without asthmatic symptoms. There were strong correlations between urinary and saliva cotinine concentrations and also, though to a lesser extent, between these media and plasma. Even a detailed questionnaire gave only a rough picture of the ETS exposure, as indicated by the biomarkers. In a multivariate model, the most significant questionnaire-derived predictor of the cotinine levels was the maternal smoking habits; other questionnaire variables gave only a minimal explained variance. Children with a history of asthmatic symptoms had statistically significantly lower median cotinine levels in urine and saliva compared to referent children, most likely because of the antismoking information to their parents. This should be considered in epidemiological studies of ETS risks. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1118221
- author
- Willers, Stefan
LU
; Axmon, Anna
LU
; Feyerabend, C ; Nielsen, Jörn LU ; Skarping, Gunnar LU and Skerfving, Staffan LU
- organization
- publishing date
- 2000
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Clinical Epidemiology
- volume
- 53
- issue
- 7
- pages
- 715 - 721
- publisher
- Elsevier
- external identifiers
-
- pmid:10941949
- scopus:0033868101
- ISSN
- 1878-5921
- DOI
- 10.1016/S0895-4356(99)00212-7
- language
- English
- LU publication?
- yes
- id
- 5715d9e5-2014-4a6d-a62e-31686d90f70d (old id 1118221)
- date added to LUP
- 2016-04-01 12:08:52
- date last changed
- 2022-03-28 20:56:33
@article{5715d9e5-2014-4a6d-a62e-31686d90f70d, abstract = {{To validate a detailed questionnaire for assessment of environmental tobacco smoke (ETS) exposure by the biomarker cotinine in various media, a population-based study in the urban area of Malmo, Sweden was performed in children aged 8-13 years with and without asthmatic symptoms. There were strong correlations between urinary and saliva cotinine concentrations and also, though to a lesser extent, between these media and plasma. Even a detailed questionnaire gave only a rough picture of the ETS exposure, as indicated by the biomarkers. In a multivariate model, the most significant questionnaire-derived predictor of the cotinine levels was the maternal smoking habits; other questionnaire variables gave only a minimal explained variance. Children with a history of asthmatic symptoms had statistically significantly lower median cotinine levels in urine and saliva compared to referent children, most likely because of the antismoking information to their parents. This should be considered in epidemiological studies of ETS risks.}}, author = {{Willers, Stefan and Axmon, Anna and Feyerabend, C and Nielsen, Jörn and Skarping, Gunnar and Skerfving, Staffan}}, issn = {{1878-5921}}, language = {{eng}}, number = {{7}}, pages = {{715--721}}, publisher = {{Elsevier}}, series = {{Journal of Clinical Epidemiology}}, title = {{Assessment of environmental tobacco smoke exposure in children with asthmatic symptoms by questionnaire and cotinine concentrations in plasma, saliva, and urine}}, url = {{http://dx.doi.org/10.1016/S0895-4356(99)00212-7}}, doi = {{10.1016/S0895-4356(99)00212-7}}, volume = {{53}}, year = {{2000}}, }