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Bacterial vaginosis: a threat to reproductive health? Historical perspectives, current knowledge, controversies and research demands

Mårdh, Per-Anders LU (2000) In European Journal of Contraception & Reproductive Health Care 5(3). p.208-219
Abstract
Bacterial vaginosis is a change in flora, the cause of which is still unknown in the vast majority of instances. Bacterial vaginosis has generally been used to represent any change in vaginal flora resulting in an assumed loss of lactobacilli. However, whether such a flora represents the genetically normal state of some women is poorly defined. The present 'crude' diagnosis of bacterial vaginosis ought to be refined. The proposed impact of bacterial vaginosis on adverse pregnancy outcome is contradicted by therapeutic studies involving pregnant women that result in a change in flora to a lactobacillus-dominated vaginal flora, but have no influence on the course ofpregnancy. Most therapies recommended for bacterial vaginosis in non-pregnant... (More)
Bacterial vaginosis is a change in flora, the cause of which is still unknown in the vast majority of instances. Bacterial vaginosis has generally been used to represent any change in vaginal flora resulting in an assumed loss of lactobacilli. However, whether such a flora represents the genetically normal state of some women is poorly defined. The present 'crude' diagnosis of bacterial vaginosis ought to be refined. The proposed impact of bacterial vaginosis on adverse pregnancy outcome is contradicted by therapeutic studies involving pregnant women that result in a change in flora to a lactobacillus-dominated vaginal flora, but have no influence on the course ofpregnancy. Most therapies recommended for bacterial vaginosis in non-pregnant women are often successful in the short term, but usually unsuccessful if the follow-up period after finishing therapy is prolonged. Although bacterial vaginosis is generally believed to be an endogenous condition, a number of behavioral factors are involved, such as the use of contraceptive and intimate hygiene products and smoking habits. Although bacterial vaginosis is not considered a true sexually transmitted infection, it is correlated to sexual activities. The current review elaborates on these matters and on the vaginal microbial ecology. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Contraception & Reproductive Health Care
volume
5
issue
3
pages
208 - 219
publisher
Parthenon Publishing
external identifiers
  • pmid:11131786
  • scopus:0033730217
ISSN
1362-5187
DOI
10.1080/13625180008500398
language
English
LU publication?
yes
id
896c8a3c-2f43-42a2-9c29-727cb34569d6 (old id 1118227)
date added to LUP
2008-06-18 13:43:49
date last changed
2017-08-13 03:29:43
@article{896c8a3c-2f43-42a2-9c29-727cb34569d6,
  abstract     = {Bacterial vaginosis is a change in flora, the cause of which is still unknown in the vast majority of instances. Bacterial vaginosis has generally been used to represent any change in vaginal flora resulting in an assumed loss of lactobacilli. However, whether such a flora represents the genetically normal state of some women is poorly defined. The present 'crude' diagnosis of bacterial vaginosis ought to be refined. The proposed impact of bacterial vaginosis on adverse pregnancy outcome is contradicted by therapeutic studies involving pregnant women that result in a change in flora to a lactobacillus-dominated vaginal flora, but have no influence on the course ofpregnancy. Most therapies recommended for bacterial vaginosis in non-pregnant women are often successful in the short term, but usually unsuccessful if the follow-up period after finishing therapy is prolonged. Although bacterial vaginosis is generally believed to be an endogenous condition, a number of behavioral factors are involved, such as the use of contraceptive and intimate hygiene products and smoking habits. Although bacterial vaginosis is not considered a true sexually transmitted infection, it is correlated to sexual activities. The current review elaborates on these matters and on the vaginal microbial ecology.},
  author       = {Mårdh, Per-Anders},
  issn         = {1362-5187},
  language     = {eng},
  number       = {3},
  pages        = {208--219},
  publisher    = {Parthenon Publishing},
  series       = {European Journal of Contraception & Reproductive Health Care},
  title        = {Bacterial vaginosis: a threat to reproductive health? Historical perspectives, current knowledge, controversies and research demands},
  url          = {http://dx.doi.org/10.1080/13625180008500398},
  volume       = {5},
  year         = {2000},
}