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Redox signalling in chloroplasts and mitochondria: genomic and biochemical evidence for two-component regulatory systems in bioenergetic organelles

Forsberg, Jens LU ; Rosenquist, Magnus LU ; Fraysse, Laure LU and Allen, John LU (2001) In Biochemical Society Transactions 29(4). p.403-407
Abstract
Redox chemistry is central to the primary functions of chloroplasts and mitochondria, that is, to energy conversion in photosynthesis and respiration. However, these bioenergetic organelles always contain very small, specialized genetic systems, relics of their bacterial origin. At huge cost, organellar genomes contain, typically, a mere 0.1% of the genetic information in a eukaryotic cell. There is evidence that chloroplast and mitochondrial genomes encode proteins whose function and biogenesis are particularly tightly governed by electron transfer. We have identified nuclear genes for 'bacterial' histidine sensor kinases and aspartate response regulators that seem to be targeted to chloroplast and mitochondrial membranes. Sequence... (More)
Redox chemistry is central to the primary functions of chloroplasts and mitochondria, that is, to energy conversion in photosynthesis and respiration. However, these bioenergetic organelles always contain very small, specialized genetic systems, relics of their bacterial origin. At huge cost, organellar genomes contain, typically, a mere 0.1% of the genetic information in a eukaryotic cell. There is evidence that chloroplast and mitochondrial genomes encode proteins whose function and biogenesis are particularly tightly governed by electron transfer. We have identified nuclear genes for 'bacterial' histidine sensor kinases and aspartate response regulators that seem to be targeted to chloroplast and mitochondrial membranes. Sequence similarities to cyanobacterial redox signalling components indicate homology and suggest conserved sensory and signalling functions. Two-component redox signalling pathways might be ancient, conserved mechanisms that permit endogenous control over the biogenesis, in situ, of bioenergetic complexes of chloroplasts and mitochondria. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Biochemical Society Transactions
volume
29
issue
4
pages
403 - 407
publisher
Biochemical Society
external identifiers
  • wos:000170780000007
  • scopus:0034859137
ISSN
0300-5127
language
English
LU publication?
yes
id
b77cf787-52f4-485a-b6ae-68b954a67c38 (old id 1118963)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/11497997
date added to LUP
2008-06-27 11:42:26
date last changed
2018-05-29 10:16:50
@article{b77cf787-52f4-485a-b6ae-68b954a67c38,
  abstract     = {Redox chemistry is central to the primary functions of chloroplasts and mitochondria, that is, to energy conversion in photosynthesis and respiration. However, these bioenergetic organelles always contain very small, specialized genetic systems, relics of their bacterial origin. At huge cost, organellar genomes contain, typically, a mere 0.1% of the genetic information in a eukaryotic cell. There is evidence that chloroplast and mitochondrial genomes encode proteins whose function and biogenesis are particularly tightly governed by electron transfer. We have identified nuclear genes for 'bacterial' histidine sensor kinases and aspartate response regulators that seem to be targeted to chloroplast and mitochondrial membranes. Sequence similarities to cyanobacterial redox signalling components indicate homology and suggest conserved sensory and signalling functions. Two-component redox signalling pathways might be ancient, conserved mechanisms that permit endogenous control over the biogenesis, in situ, of bioenergetic complexes of chloroplasts and mitochondria.},
  author       = {Forsberg, Jens and Rosenquist, Magnus and Fraysse, Laure and Allen, John},
  issn         = {0300-5127},
  language     = {eng},
  number       = {4},
  pages        = {403--407},
  publisher    = {Biochemical Society},
  series       = {Biochemical Society Transactions},
  title        = {Redox signalling in chloroplasts and mitochondria: genomic and biochemical evidence for two-component regulatory systems in bioenergetic organelles},
  volume       = {29},
  year         = {2001},
}