Redox signalling in chloroplasts and mitochondria: genomic and biochemical evidence for two-component regulatory systems in bioenergetic organelles
(2001) In Biochemical Society Transactions 29(4). p.403-407- Abstract
- Redox chemistry is central to the primary functions of chloroplasts and mitochondria, that is, to energy conversion in photosynthesis and respiration. However, these bioenergetic organelles always contain very small, specialized genetic systems, relics of their bacterial origin. At huge cost, organellar genomes contain, typically, a mere 0.1% of the genetic information in a eukaryotic cell. There is evidence that chloroplast and mitochondrial genomes encode proteins whose function and biogenesis are particularly tightly governed by electron transfer. We have identified nuclear genes for 'bacterial' histidine sensor kinases and aspartate response regulators that seem to be targeted to chloroplast and mitochondrial membranes. Sequence... (More)
- Redox chemistry is central to the primary functions of chloroplasts and mitochondria, that is, to energy conversion in photosynthesis and respiration. However, these bioenergetic organelles always contain very small, specialized genetic systems, relics of their bacterial origin. At huge cost, organellar genomes contain, typically, a mere 0.1% of the genetic information in a eukaryotic cell. There is evidence that chloroplast and mitochondrial genomes encode proteins whose function and biogenesis are particularly tightly governed by electron transfer. We have identified nuclear genes for 'bacterial' histidine sensor kinases and aspartate response regulators that seem to be targeted to chloroplast and mitochondrial membranes. Sequence similarities to cyanobacterial redox signalling components indicate homology and suggest conserved sensory and signalling functions. Two-component redox signalling pathways might be ancient, conserved mechanisms that permit endogenous control over the biogenesis, in situ, of bioenergetic complexes of chloroplasts and mitochondria. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1118963
- author
- Forsberg, Jens LU ; Rosenquist, Magnus LU ; Fraysse, Laure LU and Allen, John LU
- organization
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Biochemical Society Transactions
- volume
- 29
- issue
- 4
- pages
- 403 - 407
- publisher
- Biochemical Society
- external identifiers
-
- wos:000170780000007
- scopus:0034859137
- ISSN
- 0300-5127
- language
- English
- LU publication?
- yes
- id
- b77cf787-52f4-485a-b6ae-68b954a67c38 (old id 1118963)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/11497997
- date added to LUP
- 2016-04-01 12:35:26
- date last changed
- 2022-04-21 17:33:17
@article{b77cf787-52f4-485a-b6ae-68b954a67c38,
abstract = {{Redox chemistry is central to the primary functions of chloroplasts and mitochondria, that is, to energy conversion in photosynthesis and respiration. However, these bioenergetic organelles always contain very small, specialized genetic systems, relics of their bacterial origin. At huge cost, organellar genomes contain, typically, a mere 0.1% of the genetic information in a eukaryotic cell. There is evidence that chloroplast and mitochondrial genomes encode proteins whose function and biogenesis are particularly tightly governed by electron transfer. We have identified nuclear genes for 'bacterial' histidine sensor kinases and aspartate response regulators that seem to be targeted to chloroplast and mitochondrial membranes. Sequence similarities to cyanobacterial redox signalling components indicate homology and suggest conserved sensory and signalling functions. Two-component redox signalling pathways might be ancient, conserved mechanisms that permit endogenous control over the biogenesis, in situ, of bioenergetic complexes of chloroplasts and mitochondria.}},
author = {{Forsberg, Jens and Rosenquist, Magnus and Fraysse, Laure and Allen, John}},
issn = {{0300-5127}},
language = {{eng}},
number = {{4}},
pages = {{403--407}},
publisher = {{Biochemical Society}},
series = {{Biochemical Society Transactions}},
title = {{Redox signalling in chloroplasts and mitochondria: genomic and biochemical evidence for two-component regulatory systems in bioenergetic organelles}},
url = {{http://www.ncbi.nlm.nih.gov/pubmed/11497997}},
volume = {{29}},
year = {{2001}},
}