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Work-related psychosocial factors and carotid atherosclerosis.

Rosvall, M; Östergren, Per-Olof LU ; Hedblad, Bo LU ; Isacsson, Sven-Olof LU ; Janzon, Lars LU and Berglund, Göran LU (2002) In International Journal of Epidemiology 31(6). p.1169-1178
Abstract
Background In order to better understand the role of work environment in the earlier stages of the cardiovascular disease process, we wanted to investigate the influence of work-related psychosocial factors on preclinical atherosclerosis.



Methods Cross-sectional data was used to examine the association between psychological job demands, job decision latitude, and carotid atherosclerosis in 2658 vocationally-active Swedish men and women, ages 46–65, from the general population. Odds ratios of carotid plaque prevalence and carotid artery intima-media thickness (IMT), determined by B-mode ultrasound, were estimated across combinations of job demands and decision latitude.



Results Women in job situations... (More)
Background In order to better understand the role of work environment in the earlier stages of the cardiovascular disease process, we wanted to investigate the influence of work-related psychosocial factors on preclinical atherosclerosis.



Methods Cross-sectional data was used to examine the association between psychological job demands, job decision latitude, and carotid atherosclerosis in 2658 vocationally-active Swedish men and women, ages 46–65, from the general population. Odds ratios of carotid plaque prevalence and carotid artery intima-media thickness (IMT), determined by B-mode ultrasound, were estimated across combinations of job demands and decision latitude.



Results Women in job situations with high demands and low decision latitude (‘job strain’) showed a high plaque prevalence odds (odds ratio [OR] = 1.68, 95% CI: 1.14, 2.48), and a thicker IMT in the carotid bifurcation area (mean difference: 0.15 mm, 95% CI: 0.07, 0.23) compared with women in job situations with low demands and high decision latitude (‘relaxed’). Adjustment for covariates only slightly reduced the magnitude of these associations. No such associations were seen in men. However, women in job situations with high demands and high decision latitude (‘active’) also showed high odds for carotid plaque, and a thicker IMT in the carotid bifurcation, compared with women in ‘relaxed’ job situations. In men, those in ‘active’ job situations had a low carotid plaque prevalence odds, while IMT in the carotid bifurcation did not differ from those in ‘relaxed’ job situations. Results showed only weak associations with IMT in the common carotid artery (CCA) in both men and women.



Conclusion The specific hypothesis that high job demands interact synergistically with low decision latitude in the development of carotid atherosclerosis could not be supported in this study, neither in men nor in women. Instead a more complex pattern of interaction between job demands and decision latitude was shown. (Less)
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author
organization
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type
Contribution to journal
publication status
published
subject
in
International Journal of Epidemiology
volume
31
issue
6
pages
1169 - 1178
publisher
Oxford University Press
external identifiers
  • wos:000181279100022
  • pmid:12540718
  • scopus:0036993224
ISSN
1464-3685
DOI
10.1093/ije/31.6.1169
language
English
LU publication?
yes
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0aa4187c-3d31-47d6-b147-7fa294874847 (old id 111899)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12540718&dopt=Abstract
date added to LUP
2007-07-06 11:15:47
date last changed
2017-11-19 03:37:12
@article{0aa4187c-3d31-47d6-b147-7fa294874847,
  abstract     = {Background In order to better understand the role of work environment in the earlier stages of the cardiovascular disease process, we wanted to investigate the influence of work-related psychosocial factors on preclinical atherosclerosis.<br/><br>
<br/><br>
Methods Cross-sectional data was used to examine the association between psychological job demands, job decision latitude, and carotid atherosclerosis in 2658 vocationally-active Swedish men and women, ages 46–65, from the general population. Odds ratios of carotid plaque prevalence and carotid artery intima-media thickness (IMT), determined by B-mode ultrasound, were estimated across combinations of job demands and decision latitude.<br/><br>
<br/><br>
Results Women in job situations with high demands and low decision latitude (‘job strain’) showed a high plaque prevalence odds (odds ratio [OR] = 1.68, 95% CI: 1.14, 2.48), and a thicker IMT in the carotid bifurcation area (mean difference: 0.15 mm, 95% CI: 0.07, 0.23) compared with women in job situations with low demands and high decision latitude (‘relaxed’). Adjustment for covariates only slightly reduced the magnitude of these associations. No such associations were seen in men. However, women in job situations with high demands and high decision latitude (‘active’) also showed high odds for carotid plaque, and a thicker IMT in the carotid bifurcation, compared with women in ‘relaxed’ job situations. In men, those in ‘active’ job situations had a low carotid plaque prevalence odds, while IMT in the carotid bifurcation did not differ from those in ‘relaxed’ job situations. Results showed only weak associations with IMT in the common carotid artery (CCA) in both men and women.<br/><br>
<br/><br>
Conclusion The specific hypothesis that high job demands interact synergistically with low decision latitude in the development of carotid atherosclerosis could not be supported in this study, neither in men nor in women. Instead a more complex pattern of interaction between job demands and decision latitude was shown.},
  author       = {Rosvall, M and Östergren, Per-Olof and Hedblad, Bo and Isacsson, Sven-Olof and Janzon, Lars and Berglund, Göran},
  issn         = {1464-3685},
  language     = {eng},
  number       = {6},
  pages        = {1169--1178},
  publisher    = {Oxford University Press},
  series       = {International Journal of Epidemiology},
  title        = {Work-related psychosocial factors and carotid atherosclerosis.},
  url          = {http://dx.doi.org/10.1093/ije/31.6.1169},
  volume       = {31},
  year         = {2002},
}