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Lactobacillus acidophilus autolysins inhibit Helicobacter pylori in vitro

Lorca, Graciela L.; Wadström, Torkel LU ; Font de Valdez, Graciela and Ljungh, Åsa LU (2001) In Current Microbiology 42(1). p.39-44
Abstract
Antibacterial activity of 17 strains of lactobacilli was tested against 10 strains of H. pylori. The inhibition observed was related to the acid production and the low pH attained. No relationship between CagA phenotype of H, pylori strains and tolerance to lactic acid was observed. In mixed cultures, L. acidophilus CRL 639 showed an autolytic behavior after 24 h of culture. At this moment, H. py[ori CCUG17874 showed a decrease of 2 log-cycle, and no viable count was detected after 48 h, The bactericidal effect of L. acidophilus CRL 639 in mixed cultures is related to a proteinaceous compound released after cell lysis.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Current Microbiology
volume
42
issue
1
pages
39 - 44
publisher
Springer
external identifiers
  • wos:000166244100008
  • scopus:0035100869
ISSN
0343-8651
DOI
10.1007/s002840010175
language
English
LU publication?
yes
id
14385dd0-4948-4d4b-9baa-4bca37ee9798 (old id 1119726)
date added to LUP
2008-07-04 11:45:22
date last changed
2018-07-01 04:10:50
@article{14385dd0-4948-4d4b-9baa-4bca37ee9798,
  abstract     = {Antibacterial activity of 17 strains of lactobacilli was tested against 10 strains of H. pylori. The inhibition observed was related to the acid production and the low pH attained. No relationship between CagA phenotype of H, pylori strains and tolerance to lactic acid was observed. In mixed cultures, L. acidophilus CRL 639 showed an autolytic behavior after 24 h of culture. At this moment, H. py[ori CCUG17874 showed a decrease of 2 log-cycle, and no viable count was detected after 48 h, The bactericidal effect of L. acidophilus CRL 639 in mixed cultures is related to a proteinaceous compound released after cell lysis.},
  author       = {Lorca, Graciela L. and Wadström, Torkel and Font de Valdez, Graciela and Ljungh, Åsa},
  issn         = {0343-8651},
  language     = {eng},
  number       = {1},
  pages        = {39--44},
  publisher    = {Springer},
  series       = {Current Microbiology},
  title        = {Lactobacillus acidophilus autolysins inhibit Helicobacter pylori in vitro},
  url          = {http://dx.doi.org/10.1007/s002840010175},
  volume       = {42},
  year         = {2001},
}