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Sympathetic skin vasoconstriction--further evaluation using laser Doppler techniques

Holmlund, F ; Freccero, Carolin LU ; Bornmyr, S ; Castenfors, J ; Johansson, A-M ; Nordquist, J ; Sundkvist, Göran LU ; Svensson, H and Wollmer, Per LU (2001) In Clinical Physiology 21(3). p.287-291
Abstract
The aim of this study was to quantify the reflex sympathetic vasoconstriction in skin at different depths. Twenty healthy subjects were studied. Finger skin blood flow was measured using laser Doppler perfusion imaging (LDPI) and laser Doppler perfusion monitoring (LDPM). In LDPM, a probe with fibres separated 0.25 mm (deep) and 0.14 mm (superficial) from the illuminating fibre was used. Local heating (40 degrees C) was achieved with a Peltier element, and reflex vasoconstriction induced by immersion of the contra-lateral hand and forearm for 3 min in water at 15 degrees C. The change in skin blood flow was measured and a vasoconstriction index (VAC: cooling/before cooling) calculated. VAC indices of LDPI, LDPM-0.25 and LDPM-0.14 were... (More)
The aim of this study was to quantify the reflex sympathetic vasoconstriction in skin at different depths. Twenty healthy subjects were studied. Finger skin blood flow was measured using laser Doppler perfusion imaging (LDPI) and laser Doppler perfusion monitoring (LDPM). In LDPM, a probe with fibres separated 0.25 mm (deep) and 0.14 mm (superficial) from the illuminating fibre was used. Local heating (40 degrees C) was achieved with a Peltier element, and reflex vasoconstriction induced by immersion of the contra-lateral hand and forearm for 3 min in water at 15 degrees C. The change in skin blood flow was measured and a vasoconstriction index (VAC: cooling/before cooling) calculated. VAC indices of LDPI, LDPM-0.25 and LDPM-0.14 were 0.60, 0.59 and 0.60, respectively. The two components of the LDPM perfusion value, blood cell velocity and concentration, were studied separately. Their contributions in LDPM-0.25 were roughly the same, whereas the velocity component dominated in LDPM-0.14, although their relative responses in the two channels were similar. We conclude that sympathetic skin vasoconstriction does not significantly differ in two compartments, as probed with fibres separated by 0.25 and 0.14 mm. Blood cell velocity is influenced in a proportional way, as is concentration. (Less)
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author
; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
concentration, contra-lateral cooling, fibre separation, finger skin blood flow, laser Doppler perfusion imaging, laser Doppler perfusion monitoring, local heating, measuring depth, sympathetic vasoconstriction, velocity
in
Clinical Physiology
volume
21
issue
3
pages
287 - 291
publisher
John Wiley and Sons
external identifiers
  • pmid:11380527
  • scopus:0035007388
ISSN
1365-2281
DOI
10.1046/j.1365-2281.2001.00331.x
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Reconstructive Surgery (013240300), Diabetes Epidemiology and Neuropathy (013241560), Clinical Physiology and Nuclear Medicine Unit (013242320)
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727f0bf9-6698-4858-b192-35f75662d839 (old id 1120832)
date added to LUP
2016-04-01 11:41:12
date last changed
2021-01-06 04:46:57
@article{727f0bf9-6698-4858-b192-35f75662d839,
  abstract     = {The aim of this study was to quantify the reflex sympathetic vasoconstriction in skin at different depths. Twenty healthy subjects were studied. Finger skin blood flow was measured using laser Doppler perfusion imaging (LDPI) and laser Doppler perfusion monitoring (LDPM). In LDPM, a probe with fibres separated 0.25 mm (deep) and 0.14 mm (superficial) from the illuminating fibre was used. Local heating (40 degrees C) was achieved with a Peltier element, and reflex vasoconstriction induced by immersion of the contra-lateral hand and forearm for 3 min in water at 15 degrees C. The change in skin blood flow was measured and a vasoconstriction index (VAC: cooling/before cooling) calculated. VAC indices of LDPI, LDPM-0.25 and LDPM-0.14 were 0.60, 0.59 and 0.60, respectively. The two components of the LDPM perfusion value, blood cell velocity and concentration, were studied separately. Their contributions in LDPM-0.25 were roughly the same, whereas the velocity component dominated in LDPM-0.14, although their relative responses in the two channels were similar. We conclude that sympathetic skin vasoconstriction does not significantly differ in two compartments, as probed with fibres separated by 0.25 and 0.14 mm. Blood cell velocity is influenced in a proportional way, as is concentration.},
  author       = {Holmlund, F and Freccero, Carolin and Bornmyr, S and Castenfors, J and Johansson, A-M and Nordquist, J and Sundkvist, Göran and Svensson, H and Wollmer, Per},
  issn         = {1365-2281},
  language     = {eng},
  number       = {3},
  pages        = {287--291},
  publisher    = {John Wiley and Sons},
  series       = {Clinical Physiology},
  title        = {Sympathetic skin vasoconstriction--further evaluation using laser Doppler techniques},
  url          = {http://dx.doi.org/10.1046/j.1365-2281.2001.00331.x},
  doi          = {10.1046/j.1365-2281.2001.00331.x},
  volume       = {21},
  year         = {2001},
}