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Self-reported symptoms among women after cosmetic breast implant and breast reduction surgery

Fryzek, Jon P.; Signorello, Lisa B; Hakelius, Lars; Feltelius, Nils; Ringberg, Anita LU ; Blot, William J.; McLaughlin, Joseph K. and Nyren, Olof (2001) In Plastic and Reconstructive Surgery 107(1). p.206-213
Abstract
A retrospective cohort study was performed in Sweden to evaluate the possibility that an individual symptom or constellation of illness symptoms related to silicone occurs in women after breast implant surgery. A random sample (n = 2500) of all women in the Swedish national implant registry who underwent breast augmentation surgery with alloplastic breast implants during the years 1965 through 1993 was compared with a sample (n = 3500) of women who underwent breast reduction surgery during the same period, frequency matched to the implant patients for age and calendar year at the time of surgery. In total, 65 percent of the breast implant patients (n = 1546) and 72 percent of the breast reduction patients (n = 2496) completed a... (More)
A retrospective cohort study was performed in Sweden to evaluate the possibility that an individual symptom or constellation of illness symptoms related to silicone occurs in women after breast implant surgery. A random sample (n = 2500) of all women in the Swedish national implant registry who underwent breast augmentation surgery with alloplastic breast implants during the years 1965 through 1993 was compared with a sample (n = 3500) of women who underwent breast reduction surgery during the same period, frequency matched to the implant patients for age and calendar year at the time of surgery. In total, 65 percent of the breast implant patients (n = 1546) and 72 percent of the breast reduction patients (n = 2496) completed a self-administered questionnaire covering 28 rheumatologic and other symptoms and lifestyle and demographic factors. Practically all of the 28 symptoms inquired about were reported more often by women in the breast implant cohort, with 16 (57 percent) significantly more common in breast implant recipients. In contrast, few significant differences or consistent patterns were observed in the length of time since the implant and in the type (silicone or saline) or volume of the implant. Although women with breast implants report a multitude of symptoms more often than women who have breast reduction surgery, the lack of specificity and absence of dose-response relationships suggest that the excess of reported symptoms is not causally related to cosmetic implants. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Plastic and Reconstructive Surgery
volume
107
issue
1
pages
206 - 213
publisher
Lippincott Williams & Wilkins
external identifiers
  • pmid:11176625
  • scopus:0035165526
ISSN
0032-1052
language
English
LU publication?
yes
id
418483c6-0dcf-45da-a6cb-311c34413842 (old id 1120849)
date added to LUP
2008-06-27 13:55:13
date last changed
2018-05-29 10:27:56
@article{418483c6-0dcf-45da-a6cb-311c34413842,
  abstract     = {A retrospective cohort study was performed in Sweden to evaluate the possibility that an individual symptom or constellation of illness symptoms related to silicone occurs in women after breast implant surgery. A random sample (n = 2500) of all women in the Swedish national implant registry who underwent breast augmentation surgery with alloplastic breast implants during the years 1965 through 1993 was compared with a sample (n = 3500) of women who underwent breast reduction surgery during the same period, frequency matched to the implant patients for age and calendar year at the time of surgery. In total, 65 percent of the breast implant patients (n = 1546) and 72 percent of the breast reduction patients (n = 2496) completed a self-administered questionnaire covering 28 rheumatologic and other symptoms and lifestyle and demographic factors. Practically all of the 28 symptoms inquired about were reported more often by women in the breast implant cohort, with 16 (57 percent) significantly more common in breast implant recipients. In contrast, few significant differences or consistent patterns were observed in the length of time since the implant and in the type (silicone or saline) or volume of the implant. Although women with breast implants report a multitude of symptoms more often than women who have breast reduction surgery, the lack of specificity and absence of dose-response relationships suggest that the excess of reported symptoms is not causally related to cosmetic implants.},
  author       = {Fryzek, Jon P. and Signorello, Lisa B and Hakelius, Lars and Feltelius, Nils and Ringberg, Anita and Blot, William J. and McLaughlin, Joseph K. and Nyren, Olof},
  issn         = {0032-1052},
  language     = {eng},
  number       = {1},
  pages        = {206--213},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {Plastic and Reconstructive Surgery},
  title        = {Self-reported symptoms among women after cosmetic breast implant and breast reduction surgery},
  volume       = {107},
  year         = {2001},
}