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Influence of factor V Leiden on the development of neovascularisation secondary to central retinal vein occlusion.

Lindberg, Charlotte LU ; Hillarp, Andreas LU and Larsson, Jörgen LU (2003) In British Journal of Ophthalmology 87(3). p.305-306
Abstract
Aims: To investigate if the presence of factor V Leiden has an influence on the prognosis in central retinal vein occlusion (CRVO).



Methods: 166 patients with CRVO were studied retrospectively. They were tested for factor V Leiden using DNA analysis. The presence of the mutation was studied in correlation with the development of neovascular complications 1 year after the thrombotic event.



Results: 56 of 166 patients (34%) developed neovascular complications after 1 year. In the patients who had the studied mutation 11 of 20 (55%) had developed neovascular complications after 1 year, compared to 45 of 146 patients (31%) in the group without factor V Leiden (p=0.04).



Conclusion: The... (More)
Aims: To investigate if the presence of factor V Leiden has an influence on the prognosis in central retinal vein occlusion (CRVO).



Methods: 166 patients with CRVO were studied retrospectively. They were tested for factor V Leiden using DNA analysis. The presence of the mutation was studied in correlation with the development of neovascular complications 1 year after the thrombotic event.



Results: 56 of 166 patients (34%) developed neovascular complications after 1 year. In the patients who had the studied mutation 11 of 20 (55%) had developed neovascular complications after 1 year, compared to 45 of 146 patients (31%) in the group without factor V Leiden (p=0.04).



Conclusion: The presence of factor V Leiden seems to enhance the risk of developing neovascular complications in CRVO. (Less)
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author
organization
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type
Contribution to journal
publication status
published
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in
British Journal of Ophthalmology
volume
87
issue
3
pages
305 - 306
publisher
BMJ Publishing Group
external identifiers
  • pmid:12598443
  • wos:000181368500015
  • scopus:0037340035
ISSN
1468-2079
DOI
language
English
LU publication?
yes
id
c821543c-79e2-4cc8-96c7-3f5a8f69846f (old id 112250)
alternative location
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=12598443&dopt=Abstract
date added to LUP
2007-07-09 09:29:04
date last changed
2018-05-29 10:21:10
@article{c821543c-79e2-4cc8-96c7-3f5a8f69846f,
  abstract     = {Aims: To investigate if the presence of factor V Leiden has an influence on the prognosis in central retinal vein occlusion (CRVO). <br/><br>
<br/><br>
Methods: 166 patients with CRVO were studied retrospectively. They were tested for factor V Leiden using DNA analysis. The presence of the mutation was studied in correlation with the development of neovascular complications 1 year after the thrombotic event. <br/><br>
<br/><br>
Results: 56 of 166 patients (34%) developed neovascular complications after 1 year. In the patients who had the studied mutation 11 of 20 (55%) had developed neovascular complications after 1 year, compared to 45 of 146 patients (31%) in the group without factor V Leiden (p=0.04). <br/><br>
<br/><br>
Conclusion: The presence of factor V Leiden seems to enhance the risk of developing neovascular complications in CRVO.},
  author       = {Lindberg, Charlotte and Hillarp, Andreas and Larsson, Jörgen},
  issn         = {1468-2079},
  language     = {eng},
  number       = {3},
  pages        = {305--306},
  publisher    = {BMJ Publishing Group},
  series       = {British Journal of Ophthalmology},
  title        = {Influence of factor V Leiden on the development of neovascularisation secondary to central retinal vein occlusion.},
  url          = {http://dx.doi.org/},
  volume       = {87},
  year         = {2003},
}