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Low incidence of toxoplasma infection during pregnancy and in newborn in Sweden

Evengård, B; Pettersson, K; Engman, ML; Wiklund, Sven LU ; Ivarsson, SA; Teär-Fahnehjelm, K; Forsgren, M; Gilbert, R and Malm, G (2001) In Epidemiology and Infection 127(1). p.121-127
Abstract
To estimate the burden of disease due to congenital toxoplasmosis in Sweden the incidence of

primary infections during pregnancy and birth prevalence of congenital toxoplasmosis in 40978

children born in two regions in Sweden was determined. Women possibly infected during

pregnancy were identi®ed based on: 1, detection of speci®c IgG based on neonatal screening of

the phenylketonuria (PKU) card blood spot followed by retrospective testing of stored prenatal

samples to detect women who acquired infection during pregnancy and follow up of their

children to 12 months; 2, detection of speci®c IgM on the PKU blood spot.

The birth prevalence of congenital toxoplasmosis was 0±73}10000... (More)
To estimate the burden of disease due to congenital toxoplasmosis in Sweden the incidence of

primary infections during pregnancy and birth prevalence of congenital toxoplasmosis in 40978

children born in two regions in Sweden was determined. Women possibly infected during

pregnancy were identi®ed based on: 1, detection of speci®c IgG based on neonatal screening of

the phenylketonuria (PKU) card blood spot followed by retrospective testing of stored prenatal

samples to detect women who acquired infection during pregnancy and follow up of their

children to 12 months; 2, detection of speci®c IgM on the PKU blood spot.

The birth prevalence of congenital toxoplasmosis was 0±73}10000 (95% CI

0±15±2±14) (3}40978).

The incidence of primary infection during pregnancy was 5±1}10000 (95% CI 2±6±8±9)

susceptible pregnant women. The seroprevalence in the southern part was 25±7% and in the

Stockholm area 14±0%.

The incidence of infection during pregnancy was low, as the birth prevalence of congenital

toxoplasmosis. Neonatal screening warrants consideration in view of the low cost and

feasibility. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Epidemiology and Infection
volume
127
issue
1
pages
121 - 127
publisher
Cambridge University Press
external identifiers
  • scopus:0034839540
ISSN
0950-2688
DOI
10.1017/S0950268801005775
language
English
LU publication?
yes
id
b65ce276-14ce-4884-9841-bb44f872a0da (old id 1122626)
date added to LUP
2008-06-27 09:57:16
date last changed
2018-08-12 03:29:29
@article{b65ce276-14ce-4884-9841-bb44f872a0da,
  abstract     = {To estimate the burden of disease due to congenital toxoplasmosis in Sweden the incidence of<br/><br>
primary infections during pregnancy and birth prevalence of congenital toxoplasmosis in 40978<br/><br>
children born in two regions in Sweden was determined. Women possibly infected during<br/><br>
pregnancy were identi®ed based on: 1, detection of speci®c IgG based on neonatal screening of<br/><br>
the phenylketonuria (PKU) card blood spot followed by retrospective testing of stored prenatal<br/><br>
samples to detect women who acquired infection during pregnancy and follow up of their<br/><br>
children to 12 months; 2, detection of speci®c IgM on the PKU blood spot.<br/><br>
The birth prevalence of congenital toxoplasmosis was 0±73}10000 (95% CI<br/><br>
0±15±2±14) (3}40978).<br/><br>
The incidence of primary infection during pregnancy was 5±1}10000 (95% CI 2±6±8±9)<br/><br>
susceptible pregnant women. The seroprevalence in the southern part was 25±7% and in the<br/><br>
Stockholm area 14±0%.<br/><br>
The incidence of infection during pregnancy was low, as the birth prevalence of congenital<br/><br>
toxoplasmosis. Neonatal screening warrants consideration in view of the low cost and<br/><br>
feasibility.},
  author       = {Evengård, B and Pettersson, K and Engman, ML and Wiklund, Sven and Ivarsson, SA and Teär-Fahnehjelm, K and Forsgren, M and Gilbert, R and Malm, G},
  issn         = {0950-2688},
  language     = {eng},
  number       = {1},
  pages        = {121--127},
  publisher    = {Cambridge University Press},
  series       = {Epidemiology and Infection},
  title        = {Low incidence of toxoplasma infection during pregnancy and in newborn in Sweden},
  url          = {http://dx.doi.org/10.1017/S0950268801005775},
  volume       = {127},
  year         = {2001},
}