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Fetal varicella-herpes zoster syndrome in early pregnancy: ultrasonographic and morphological correlation

Petignat, Patrick; Vial, Yvan; Laurini, Ricardo LU and Hohlfeld, Patrick (2001) In Prenatal Diagnosis 21(2). p.121-124
Abstract
We report a case of an intrauterine fetal infection by the varicella-herpes zoster virus following maternal varicella at 17 weeks' amenorrhea. Prenatal diagnosis of fetal infection was confirmed by serology and fetal damage by ultrasonography. Autopsy of the fetus showed multiorgan manifestation with disseminated foci of necrosis and microcalcifications, encephalitis and unilateral segmental skin scarring with an underlying hypoplastic fixed lower limb. The placenta showed a multifocal chronic villitis with multinucleated giant cells. The lesions included segmental anomalies and multiorgan damage.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
varicella zoster virus, prenatal diagnosis, placenta
in
Prenatal Diagnosis
volume
21
issue
2
pages
121 - 124
publisher
John Wiley and Sons Ltd
external identifiers
  • pmid:11241539
  • scopus:0035106899
ISSN
1097-0223
DOI
10.1002/1097-0223(200102)21:2<121::AID-PD996>3.0.CO;2-P
language
English
LU publication?
yes
id
86f854f1-8aa5-4bc2-919a-cb2d7cebf6f2 (old id 1123007)
date added to LUP
2008-07-10 09:31:00
date last changed
2018-05-29 11:09:52
@article{86f854f1-8aa5-4bc2-919a-cb2d7cebf6f2,
  abstract     = {We report a case of an intrauterine fetal infection by the varicella-herpes zoster virus following maternal varicella at 17 weeks' amenorrhea. Prenatal diagnosis of fetal infection was confirmed by serology and fetal damage by ultrasonography. Autopsy of the fetus showed multiorgan manifestation with disseminated foci of necrosis and microcalcifications, encephalitis and unilateral segmental skin scarring with an underlying hypoplastic fixed lower limb. The placenta showed a multifocal chronic villitis with multinucleated giant cells. The lesions included segmental anomalies and multiorgan damage.},
  author       = {Petignat, Patrick and Vial, Yvan and Laurini, Ricardo and Hohlfeld, Patrick},
  issn         = {1097-0223},
  keyword      = {varicella zoster virus,prenatal diagnosis,placenta},
  language     = {eng},
  number       = {2},
  pages        = {121--124},
  publisher    = {John Wiley and Sons Ltd},
  series       = {Prenatal Diagnosis},
  title        = {Fetal varicella-herpes zoster syndrome in early pregnancy: ultrasonographic and morphological correlation},
  url          = {http://dx.doi.org/10.1002/1097-0223(200102)21:2<121::AID-PD996>3.0.CO;2-P},
  volume       = {21},
  year         = {2001},
}