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Atrial fibrillation--Where do we stand today?

Olsson, Bertil LU (2001) In Journal of Internal Medicine1989-01-01+01:00 250(1). p.19-28
Abstract
The basic underlying mechanisms behind atrial fibrillation (AF), the most abundant therapy demanding cardiac dysrhythmia, have until recently being largely unknown. Once established, AF is not only self-perpetuating but also self-destructive, prompting rapid treatment against possible initiating mechanisms. Recent observations reveal that the ectopic beats, initiating AF, often originate in the walls of the pulmonary veins and that the deterioration of the ectopic impulse to AF may be linked to an impaired inferoposterior interatrial conduction. The underlying mechanisms behind these functional defects are still obscure. The observations has however, permitted evaluation of new types of treatment, directly interfering with the newly... (More)
The basic underlying mechanisms behind atrial fibrillation (AF), the most abundant therapy demanding cardiac dysrhythmia, have until recently being largely unknown. Once established, AF is not only self-perpetuating but also self-destructive, prompting rapid treatment against possible initiating mechanisms. Recent observations reveal that the ectopic beats, initiating AF, often originate in the walls of the pulmonary veins and that the deterioration of the ectopic impulse to AF may be linked to an impaired inferoposterior interatrial conduction. The underlying mechanisms behind these functional defects are still obscure. The observations has however, permitted evaluation of new types of treatment, directly interfering with the newly verified findings. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
ablation, atrial fibrillation, atrium, heart, pacing
in
Journal of Internal Medicine1989-01-01+01:00
volume
250
issue
1
pages
19 - 28
publisher
Wiley-Blackwell Publishing Ltd
external identifiers
  • pmid:11454138
  • scopus:0035725034
ISSN
1365-2796
DOI
10.1046/j.1365-2796.2001.00853.x
language
English
LU publication?
yes
id
70c41e67-d82c-4dc0-ab33-96f3bd81954e (old id 1123110)
date added to LUP
2008-07-09 09:24:52
date last changed
2018-01-07 08:55:50
@article{70c41e67-d82c-4dc0-ab33-96f3bd81954e,
  abstract     = {The basic underlying mechanisms behind atrial fibrillation (AF), the most abundant therapy demanding cardiac dysrhythmia, have until recently being largely unknown. Once established, AF is not only self-perpetuating but also self-destructive, prompting rapid treatment against possible initiating mechanisms. Recent observations reveal that the ectopic beats, initiating AF, often originate in the walls of the pulmonary veins and that the deterioration of the ectopic impulse to AF may be linked to an impaired inferoposterior interatrial conduction. The underlying mechanisms behind these functional defects are still obscure. The observations has however, permitted evaluation of new types of treatment, directly interfering with the newly verified findings.},
  author       = {Olsson, Bertil},
  issn         = {1365-2796},
  keyword      = {ablation,atrial fibrillation,atrium,heart,pacing},
  language     = {eng},
  number       = {1},
  pages        = {19--28},
  publisher    = {Wiley-Blackwell Publishing Ltd},
  series       = {Journal of Internal Medicine1989-01-01+01:00},
  title        = {Atrial fibrillation--Where do we stand today?},
  url          = {http://dx.doi.org/10.1046/j.1365-2796.2001.00853.x},
  volume       = {250},
  year         = {2001},
}