Diurnal variations of the dominant cycle length of chronic atrial fibrillation
(2001) In American Journal of Physiology: Heart and Circulatory Physiology 280(1). p.401-406- Abstract
- High-resolution digital Holter recording was carried out in 21 patients (15 men, 64 +/- 12 yr) with chronic atrial fibrillation. Dominating atrial cycle length (DACL) was derived by frequency domain analysis of QRST-reduced electrocardiograms. Daytime mean DACL was 150 +/- 17 ms, and nighttime mean was 157 +/- 22 ms (P = 0. 0002). Diurnal fluctuation in DACL differed among patients: it tended to be virtually absent in those with a short mean DACL, but in those with longer DACL the night-day difference was as much as 23 ms (R = 0.72, P < 0.001, correlation of mean DACL to night-day difference). Mean DACL also correlated with ventricular cycle length (R = 0.40, P < 0.001), particularly at night (r = 0.49). The shorter cycle lengths... (More)
- High-resolution digital Holter recording was carried out in 21 patients (15 men, 64 +/- 12 yr) with chronic atrial fibrillation. Dominating atrial cycle length (DACL) was derived by frequency domain analysis of QRST-reduced electrocardiograms. Daytime mean DACL was 150 +/- 17 ms, and nighttime mean was 157 +/- 22 ms (P = 0. 0002). Diurnal fluctuation in DACL differed among patients: it tended to be virtually absent in those with a short mean DACL, but in those with longer DACL the night-day difference was as much as 23 ms (R = 0.72, P < 0.001, correlation of mean DACL to night-day difference). Mean DACL also correlated with ventricular cycle length (R = 0.40, P < 0.001), particularly at night (r = 0.49). The shorter cycle lengths found in this study during the day are consistent with sympathetic and/or other physiological modulation, but since increased vagal tone shortens atrial refractoriness in most models, parasympathetic influences are not likely to play a major role. Alternatively, atrial effective refractory period may not be the sole determinant of atrial cycle length during atrial fibrillation. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1123120
- author
- Meurling, Carl LU ; Waktare, J E ; Holmqvist, Fredrik LU ; Hedman, A ; Camm, A J ; Olsson, Bertil LU and Malik, M
- organization
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- in
- American Journal of Physiology: Heart and Circulatory Physiology
- volume
- 280
- issue
- 1
- pages
- 401 - 406
- publisher
- American Physiological Society
- external identifiers
-
- pmid:11123257
- scopus:0035010022
- ISSN
- 1522-1539
- language
- English
- LU publication?
- yes
- id
- 67d227a8-2ac1-46a6-9fe1-80eec7d8dd4f (old id 1123120)
- alternative location
- http://ajpheart.physiology.org/cgi/reprint/280/1/H401
- date added to LUP
- 2016-04-01 12:26:38
- date last changed
- 2022-01-27 03:49:36
@article{67d227a8-2ac1-46a6-9fe1-80eec7d8dd4f, abstract = {{High-resolution digital Holter recording was carried out in 21 patients (15 men, 64 +/- 12 yr) with chronic atrial fibrillation. Dominating atrial cycle length (DACL) was derived by frequency domain analysis of QRST-reduced electrocardiograms. Daytime mean DACL was 150 +/- 17 ms, and nighttime mean was 157 +/- 22 ms (P = 0. 0002). Diurnal fluctuation in DACL differed among patients: it tended to be virtually absent in those with a short mean DACL, but in those with longer DACL the night-day difference was as much as 23 ms (R = 0.72, P < 0.001, correlation of mean DACL to night-day difference). Mean DACL also correlated with ventricular cycle length (R = 0.40, P < 0.001), particularly at night (r = 0.49). The shorter cycle lengths found in this study during the day are consistent with sympathetic and/or other physiological modulation, but since increased vagal tone shortens atrial refractoriness in most models, parasympathetic influences are not likely to play a major role. Alternatively, atrial effective refractory period may not be the sole determinant of atrial cycle length during atrial fibrillation.}}, author = {{Meurling, Carl and Waktare, J E and Holmqvist, Fredrik and Hedman, A and Camm, A J and Olsson, Bertil and Malik, M}}, issn = {{1522-1539}}, language = {{eng}}, number = {{1}}, pages = {{401--406}}, publisher = {{American Physiological Society}}, series = {{American Journal of Physiology: Heart and Circulatory Physiology}}, title = {{Diurnal variations of the dominant cycle length of chronic atrial fibrillation}}, url = {{http://ajpheart.physiology.org/cgi/reprint/280/1/H401}}, volume = {{280}}, year = {{2001}}, }