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DNA and cell cycle analysis as prognostic indicators in breast tumors revisited

Bagwell, C B; Clark, G M; Spyratos, F; Chassevent, A; Bendahl, Pär-Ola LU ; Stal, O; Killander, D; Jourdan, M L; Romain, S and Hunsberger, B, et al. (2001) In Clinics in Laboratory Medicine 21(4). p.875-895
Abstract
Both DNA ploidy and S-phase ploidy are promising prognostic factors for node-negative breast cancer patients. Based largely on the analysis of one large study, much of the reported problems with these factors have been caused by some unappreciated complexities in categorizing DNA ploidy into low- and high-risk groups and the lack of some necessary adjustments to eliminate unwanted correlations between DNA S-phase and ploidy. When both DNA ploidy and S-phase are compensated properly, they become independent prognostic markers, forming a powerful prognostic model.
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Contribution to journal
publication status
published
subject
in
Clinics in Laboratory Medicine
volume
21
issue
4
pages
875 - 895
publisher
W B Saunders
external identifiers
  • pmid:11770293
  • scopus:0035206075
ISSN
0272-2712
language
English
LU publication?
yes
id
b4f605f6-9f53-4443-a2d4-6b7e079d46de (old id 1123130)
date added to LUP
2008-06-24 12:03:34
date last changed
2018-05-29 10:17:31
@article{b4f605f6-9f53-4443-a2d4-6b7e079d46de,
  abstract     = {Both DNA ploidy and S-phase ploidy are promising prognostic factors for node-negative breast cancer patients. Based largely on the analysis of one large study, much of the reported problems with these factors have been caused by some unappreciated complexities in categorizing DNA ploidy into low- and high-risk groups and the lack of some necessary adjustments to eliminate unwanted correlations between DNA S-phase and ploidy. When both DNA ploidy and S-phase are compensated properly, they become independent prognostic markers, forming a powerful prognostic model.},
  author       = {Bagwell, C B and Clark, G M and Spyratos, F and Chassevent, A and Bendahl, Pär-Ola and Stal, O and Killander, D and Jourdan, M L and Romain, S and Hunsberger, B and Wright, S and Baldetorp, Bo},
  issn         = {0272-2712},
  language     = {eng},
  number       = {4},
  pages        = {875--895},
  publisher    = {W B Saunders},
  series       = {Clinics in Laboratory Medicine},
  title        = {DNA and cell cycle analysis as prognostic indicators in breast tumors revisited},
  volume       = {21},
  year         = {2001},
}