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Migration as a risk factor for schizophrenia: a Danish population-based cohort study.

Cantor-Graae, Elizabeth LU ; Pedersen, Carsten Bøcker; McNeil, Thomas F and Mortensen, Preben Bo (2003) In British Journal of Psychiatry 182. p.117-122
Abstract
Background A growing body of evidence suggests that migration is a risk factor for the development of schizophrenia, although the putative mechanism remains obscure.



Aims To examine immigrant background and history of foreign residence as risk factors for schizophrenia.



Method Using data from the Danish Civil Registration System, we established a population-based cohort of 2.14 million persons resident in Denmark by their fifteenth birthday. Schizophrenia in cohort members and parental psychiatric disorder were identified by cross-linkage with the Danish Psychiatric Case Register.



Results The relative risk of developing schizophrenia was 2.45 (95% Cl 2.25-2.67) and 1.92 (95% Cl... (More)
Background A growing body of evidence suggests that migration is a risk factor for the development of schizophrenia, although the putative mechanism remains obscure.



Aims To examine immigrant background and history of foreign residence as risk factors for schizophrenia.



Method Using data from the Danish Civil Registration System, we established a population-based cohort of 2.14 million persons resident in Denmark by their fifteenth birthday. Schizophrenia in cohort members and parental psychiatric disorder were identified by cross-linkage with the Danish Psychiatric Case Register.



Results The relative risk of developing schizophrenia was 2.45 (95% Cl 2.25-2.67) and 1.92 (95% Cl 1.74-2.12) among first- and second-generation immigrants respectively, and 1.60 (95% Cl 1.25-2.05) among Danes with a history of foreign residence.



Conclusions Migration confers an increased risk for schizophrenia that is not solely attributable to selection factors and may also be independent of foreign birth. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
British Journal of Psychiatry
volume
182
pages
117 - 122
publisher
Royal College of Psychiatrists
external identifiers
  • wos:000180872200007
  • pmid:12562738
  • scopus:0037313441
ISSN
0007-1250
language
English
LU publication?
yes
id
b4e848f3-1a7e-4db7-b9b0-9700a15795a9 (old id 112377)
alternative location
http://bjp.rcpsych.org/cgi/content/abstract/182/2/117
date added to LUP
2007-07-16 16:23:05
date last changed
2018-08-05 03:31:53
@article{b4e848f3-1a7e-4db7-b9b0-9700a15795a9,
  abstract     = {Background A growing body of evidence suggests that migration is a risk factor for the development of schizophrenia, although the putative mechanism remains obscure.<br/><br>
<br/><br>
Aims To examine immigrant background and history of foreign residence as risk factors for schizophrenia.<br/><br>
<br/><br>
Method Using data from the Danish Civil Registration System, we established a population-based cohort of 2.14 million persons resident in Denmark by their fifteenth birthday. Schizophrenia in cohort members and parental psychiatric disorder were identified by cross-linkage with the Danish Psychiatric Case Register.<br/><br>
<br/><br>
Results The relative risk of developing schizophrenia was 2.45 (95% Cl 2.25-2.67) and 1.92 (95% Cl 1.74-2.12) among first- and second-generation immigrants respectively, and 1.60 (95% Cl 1.25-2.05) among Danes with a history of foreign residence.<br/><br>
<br/><br>
Conclusions Migration confers an increased risk for schizophrenia that is not solely attributable to selection factors and may also be independent of foreign birth.},
  author       = {Cantor-Graae, Elizabeth and Pedersen, Carsten Bøcker and McNeil, Thomas F and Mortensen, Preben Bo},
  issn         = {0007-1250},
  language     = {eng},
  pages        = {117--122},
  publisher    = {Royal College of Psychiatrists},
  series       = {British Journal of Psychiatry},
  title        = {Migration as a risk factor for schizophrenia: a Danish population-based cohort study.},
  volume       = {182},
  year         = {2003},
}