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Rapid test, throat culture and clinical assessment in the diagnosis of tonsillitis.

Johansson, Lennart and Månsson, Nils-Ove LU (2003) In Family Practice 20(2). p.108-111
Abstract
Objectives. Our aim was to identify a group of patients with clinical signs of tonsillitis to whom antibiotics could be prescribed without further diagnostic actions, and to compare the outcome of clinical assessment with the result of an antigen detection test using culture as the gold standard.



Methods. During two winter months, patients aged >=4 years attending for sore throat at three primary health care centres in Malmö, Sweden, were examined. Odds ratios, sensitivities, specificities and predictive values were calculated for clinical assessment and for an antigen detection test.



Results. Among the 169 participating patients, growth of group A ß-haemolytic streptococci (GAS) was found in 53... (More)
Objectives. Our aim was to identify a group of patients with clinical signs of tonsillitis to whom antibiotics could be prescribed without further diagnostic actions, and to compare the outcome of clinical assessment with the result of an antigen detection test using culture as the gold standard.



Methods. During two winter months, patients aged >=4 years attending for sore throat at three primary health care centres in Malmö, Sweden, were examined. Odds ratios, sensitivities, specificities and predictive values were calculated for clinical assessment and for an antigen detection test.



Results. Among the 169 participating patients, growth of group A ß-haemolytic streptococci (GAS) was found in 53 cultures, and 23 patients (14%) were clinically assessed as ‘absolutely positive’, representing positive clinical assessment. Nineteen had positive cultures for GAS. The sensitivity, specificity and predictive positive and negative value for the antigen detection test were 82, 96, 90 and 93%, respectively, and for positive clinical assessment 36, 97, 83 and 77%.



Conclusion. It is possible to identify a small group of patients with convincing signs of tonsillitis in which the specificity as well as the predictive positive value of the rapid test and the clinical assessment are close to equal. Antibiotics may be prescribed to these patients without further diagnostic actions.



Keywords. Antigen detection test, clinical assessment, rapid te (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Antigen detection test, clinical assessment, rapid test, streptococci, throat culture, throat infection, tonsillitis
in
Family Practice
volume
20
issue
2
pages
108 - 111
publisher
Oxford University Press
external identifiers
  • wos:000182679400002
  • pmid:12651781
  • scopus:0242417612
ISSN
1460-2229
DOI
10.1093/fampra/20.2.108
language
English
LU publication?
yes
id
654faf42-ff31-44d8-a35d-7d368939bf1d (old id 112568)
date added to LUP
2007-07-24 12:29:03
date last changed
2017-03-26 03:31:28
@article{654faf42-ff31-44d8-a35d-7d368939bf1d,
  abstract     = {Objectives. Our aim was to identify a group of patients with clinical signs of tonsillitis to whom antibiotics could be prescribed without further diagnostic actions, and to compare the outcome of clinical assessment with the result of an antigen detection test using culture as the gold standard.<br/><br>
<br/><br>
Methods. During two winter months, patients aged &gt;=4 years attending for sore throat at three primary health care centres in Malmö, Sweden, were examined. Odds ratios, sensitivities, specificities and predictive values were calculated for clinical assessment and for an antigen detection test.<br/><br>
<br/><br>
Results. Among the 169 participating patients, growth of group A ß-haemolytic streptococci (GAS) was found in 53 cultures, and 23 patients (14%) were clinically assessed as ‘absolutely positive’, representing positive clinical assessment. Nineteen had positive cultures for GAS. The sensitivity, specificity and predictive positive and negative value for the antigen detection test were 82, 96, 90 and 93%, respectively, and for positive clinical assessment 36, 97, 83 and 77%.<br/><br>
<br/><br>
Conclusion. It is possible to identify a small group of patients with convincing signs of tonsillitis in which the specificity as well as the predictive positive value of the rapid test and the clinical assessment are close to equal. Antibiotics may be prescribed to these patients without further diagnostic actions.<br/><br>
<br/><br>
Keywords. Antigen detection test, clinical assessment, rapid te},
  author       = {Johansson, Lennart and Månsson, Nils-Ove},
  issn         = {1460-2229},
  keyword      = {Antigen detection test,clinical assessment,rapid test,streptococci,throat culture,throat infection,tonsillitis},
  language     = {eng},
  number       = {2},
  pages        = {108--111},
  publisher    = {Oxford University Press},
  series       = {Family Practice},
  title        = {Rapid test, throat culture and clinical assessment in the diagnosis of tonsillitis.},
  url          = {http://dx.doi.org/10.1093/fampra/20.2.108},
  volume       = {20},
  year         = {2003},
}