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Novel properties of antimicrobial peptides

Kamysz, Wojciech; Okroj, Marcin LU and Lukasiak, Jerzy (2003) In Acta Biochimica Polonica 50(2). p.461-469
Abstract
Endogenous peptide antibiotics are known as evolutionarily old components of innate immunity. Due to interaction with cell membrane these peptides cause permeabilization of the membrane and lysis of invading microbes. However, some studies proved that antimicrobial peptides are universal multifunctional molecules and their functions extend far beyond simple antibiotics. In this review we present an overview of the general mechanism of action of antimicrobial peptides and discuss some of their additional properties, like antitumour activity, mitogenic activity, role in signal transduction pathways and adaptive immune response.
Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Biochimica Polonica
volume
50
issue
2
pages
461 - 469
publisher
Panstwowe Wydawnictwo Naukowe
external identifiers
  • pmid:12833170
  • scopus:0042381670
ISSN
0001-527X
language
English
LU publication?
no
id
d0a19069-0ab5-48ad-9c69-c0bbc01f5955 (old id 1126465)
date added to LUP
2008-06-11 11:50:00
date last changed
2018-01-14 04:02:09
@article{d0a19069-0ab5-48ad-9c69-c0bbc01f5955,
  abstract     = {Endogenous peptide antibiotics are known as evolutionarily old components of innate immunity. Due to interaction with cell membrane these peptides cause permeabilization of the membrane and lysis of invading microbes. However, some studies proved that antimicrobial peptides are universal multifunctional molecules and their functions extend far beyond simple antibiotics. In this review we present an overview of the general mechanism of action of antimicrobial peptides and discuss some of their additional properties, like antitumour activity, mitogenic activity, role in signal transduction pathways and adaptive immune response.},
  author       = {Kamysz, Wojciech and Okroj, Marcin and Lukasiak, Jerzy},
  issn         = {0001-527X},
  language     = {eng},
  number       = {2},
  pages        = {461--469},
  publisher    = {Panstwowe Wydawnictwo Naukowe},
  series       = {Acta Biochimica Polonica},
  title        = {Novel properties of antimicrobial peptides},
  volume       = {50},
  year         = {2003},
}