IdeS and SpeB: immunoglobulin-degrading cysteine proteinases of Streptococcus pyogenes.
(2003) In Current Opinion in Microbiology 6(1). p.50-55- Abstract
- The Gram-positive bacterium Streptococcus pyogenes is a major human pathogen causing substantial morbidity and mortality in society. S. pyogenes has evolved numerous molecular mechanisms to avoid the various actions of the human immune system and has established means to modulate both adaptive and innate immune responses. S. pyogenes produces and secretes proteolytic enzymes, which have an important impact on the ability of the bacteria to survive in the human host. Prominent among these are two immunoglobulin-degrading enzymes: the newly discovered streptococcal cysteine proteinase, IdeS, and the classical cysteine proteinase of S. pyogenes, SpeB.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/113010
- author
- von Pawel-Rammingen, Ulrich LU and Björck, Lars LU
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Current Opinion in Microbiology
- volume
- 6
- issue
- 1
- pages
- 50 - 55
- publisher
- Elsevier
- external identifiers
-
- wos:000182300600008
- pmid:12615219
- scopus:0037330259
- ISSN
- 1879-0364
- DOI
- 10.1016/S1369-5274(03)00003-1
- language
- English
- LU publication?
- yes
- id
- f9c2fcc1-1af4-4bb5-bb18-8ecd506be5b8 (old id 113010)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12615219&dopt=Abstract
- date added to LUP
- 2016-04-01 11:50:04
- date last changed
- 2022-03-28 03:42:55
@article{f9c2fcc1-1af4-4bb5-bb18-8ecd506be5b8,
abstract = {{The Gram-positive bacterium Streptococcus pyogenes is a major human pathogen causing substantial morbidity and mortality in society. S. pyogenes has evolved numerous molecular mechanisms to avoid the various actions of the human immune system and has established means to modulate both adaptive and innate immune responses. S. pyogenes produces and secretes proteolytic enzymes, which have an important impact on the ability of the bacteria to survive in the human host. Prominent among these are two immunoglobulin-degrading enzymes: the newly discovered streptococcal cysteine proteinase, IdeS, and the classical cysteine proteinase of S. pyogenes, SpeB.}},
author = {{von Pawel-Rammingen, Ulrich and Björck, Lars}},
issn = {{1879-0364}},
language = {{eng}},
number = {{1}},
pages = {{50--55}},
publisher = {{Elsevier}},
series = {{Current Opinion in Microbiology}},
title = {{IdeS and SpeB: immunoglobulin-degrading cysteine proteinases of Streptococcus pyogenes.}},
url = {{http://dx.doi.org/10.1016/S1369-5274(03)00003-1}},
doi = {{10.1016/S1369-5274(03)00003-1}},
volume = {{6}},
year = {{2003}},
}