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Auditory hemodynamic studies of newborn infants using near-infrared spectroscopic imaging

Nissila, I; Kotilahti, K; Huotilainen, M; Makela, R; Lipiainen, L; Noponen, T; Gavrielides, N; Naatanen, R; Fellman, Vineta LU and Katila, T (2004) In IEEE Engineering in Medicine and Biology Society. Conference Proceedings 2. p.1244-1274
Abstract
The noninvasive study of tissue blood volume and oxygenation using near-infrared light is a new and actively developing technology. We have used near-infrared spectroscopic imaging (NIRSI) to study hemodynamic responses on the auditory cortices evoked by auditory stimulation. Ten healthy newborn infants were studied. The otoacoustic emission hearing test was performed for each infant. Pulse oximetry was used to monitor the heart rate during the measurement, video recording was used to monitor motion artifacts, and the eye movements were noted in order to determine sleep stage. A 16-channel frequency-domain optical imaging system developed in our laboratory was used for NIRSI measurements. The stimuli were presented in trains of seven 1 kHz... (More)
The noninvasive study of tissue blood volume and oxygenation using near-infrared light is a new and actively developing technology. We have used near-infrared spectroscopic imaging (NIRSI) to study hemodynamic responses on the auditory cortices evoked by auditory stimulation. Ten healthy newborn infants were studied. The otoacoustic emission hearing test was performed for each infant. Pulse oximetry was used to monitor the heart rate during the measurement, video recording was used to monitor motion artifacts, and the eye movements were noted in order to determine sleep stage. A 16-channel frequency-domain optical imaging system developed in our laboratory was used for NIRSI measurements. The stimuli were presented in trains of seven 1 kHz beeps with 700-ms inter-stimulus intervals. The stimulus trains were separated by 25-s silent periods in order to allow for the hemodynamic delay. In 3/8 cases, we obtained a clear bilateral increase in [HbO/sub 2/], and in two additional cases, a clear response on one hemisphere. The mean change in [HbO/sub 2/] was +0.9+/-0.9muM and the mean change in [Hb] was -0.3+/-0.4muM for those channels producing the largest response for each subject. No statistically significant response was found in 3/8 cases. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
IEEE Engineering in Medicine and Biology Society. Conference Proceedings
volume
2
pages
1244 - 1274
publisher
IEEE--Institute of Electrical and Electronics Engineers Inc.
external identifiers
  • pmid:17271914
  • scopus:19944424767
ISSN
1557-170X
DOI
10.1109/IEMBS.2004.1403395
language
English
LU publication?
yes
id
4c1ad906-ae28-4673-a277-6b29d7f9eb86 (old id 1130220)
date added to LUP
2008-06-17 11:38:56
date last changed
2017-01-01 07:03:21
@article{4c1ad906-ae28-4673-a277-6b29d7f9eb86,
  abstract     = {The noninvasive study of tissue blood volume and oxygenation using near-infrared light is a new and actively developing technology. We have used near-infrared spectroscopic imaging (NIRSI) to study hemodynamic responses on the auditory cortices evoked by auditory stimulation. Ten healthy newborn infants were studied. The otoacoustic emission hearing test was performed for each infant. Pulse oximetry was used to monitor the heart rate during the measurement, video recording was used to monitor motion artifacts, and the eye movements were noted in order to determine sleep stage. A 16-channel frequency-domain optical imaging system developed in our laboratory was used for NIRSI measurements. The stimuli were presented in trains of seven 1 kHz beeps with 700-ms inter-stimulus intervals. The stimulus trains were separated by 25-s silent periods in order to allow for the hemodynamic delay. In 3/8 cases, we obtained a clear bilateral increase in [HbO/sub 2/], and in two additional cases, a clear response on one hemisphere. The mean change in [HbO/sub 2/] was +0.9+/-0.9muM and the mean change in [Hb] was -0.3+/-0.4muM for those channels producing the largest response for each subject. No statistically significant response was found in 3/8 cases.},
  author       = {Nissila, I and Kotilahti, K and Huotilainen, M and Makela, R and Lipiainen, L and Noponen, T and Gavrielides, N and Naatanen, R and Fellman, Vineta and Katila, T},
  issn         = {1557-170X},
  language     = {eng},
  pages        = {1244--1274},
  publisher    = {IEEE--Institute of Electrical and Electronics Engineers Inc.},
  series       = {IEEE Engineering in Medicine and Biology Society. Conference Proceedings},
  title        = {Auditory hemodynamic studies of newborn infants using near-infrared spectroscopic imaging},
  url          = {http://dx.doi.org/10.1109/IEMBS.2004.1403395},
  volume       = {2},
  year         = {2004},
}