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Diagnostics of pulmonary embolism with emphasis of ventilation/perfusion scintigraphy and dead space analysis

Jonson, Björn LU and Bajc, Marika LU (2006) In Journal of Organ Dysfuntion 2(4). p.237-243
Abstract
Ventilation/perfusion scintigraphy, a first hand method for diagnosis of pulmonary embolism, PE, is challenged by tomography of the pulmonary arteries, CT. An additional method is based upon dead space analysis. Tomographic ventilation/perfusion scintigraphy, V/PSPECT is superior to planar technique. Important is interpretation criteria based upon pattern recognition and clinical information. With optimal strategy, the rate of non-diagnostic findings is only about 1%. The sensitivity of CT is too low to exclude subsegmental PE,. The radiation dose is for CT is several times higher than for V/PSPECT. Quantification of PE, only offered by V/PSPECT has impact on therapy and is vital for follow up. Limited availability of V/PSPECT makes CT an... (More)
Ventilation/perfusion scintigraphy, a first hand method for diagnosis of pulmonary embolism, PE, is challenged by tomography of the pulmonary arteries, CT. An additional method is based upon dead space analysis. Tomographic ventilation/perfusion scintigraphy, V/PSPECT is superior to planar technique. Important is interpretation criteria based upon pattern recognition and clinical information. With optimal strategy, the rate of non-diagnostic findings is only about 1%. The sensitivity of CT is too low to exclude subsegmental PE,. The radiation dose is for CT is several times higher than for V/PSPECT. Quantification of PE, only offered by V/PSPECT has impact on therapy and is vital for follow up. Limited availability of V/PSPECT makes CT an essential element in a strategy for diagnosis of PE. The single breath test for CO2 offers an alternative when imaging techniques are not available or when radiation is a particular problem in early pregnancy. (Less)
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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Pulmonary embolism, scintigraphy, computer tomography, dead space, radiation dose
in
Journal of Organ Dysfuntion
volume
2
issue
4
pages
237 - 243
publisher
Informa Healthcare
external identifiers
  • scopus:33751177536
ISSN
1747-1060
DOI
10.1080/17471060600580649
language
English
LU publication?
yes
id
35f38f03-8730-4a5c-9eaf-c0b41f686cee (old id 1136903)
date added to LUP
2016-04-01 11:43:41
date last changed
2020-01-12 08:29:20
@article{35f38f03-8730-4a5c-9eaf-c0b41f686cee,
  abstract     = {Ventilation/perfusion scintigraphy, a first hand method for diagnosis of pulmonary embolism, PE, is challenged by tomography of the pulmonary arteries, CT. An additional method is based upon dead space analysis. Tomographic ventilation/perfusion scintigraphy, V/PSPECT is superior to planar technique. Important is interpretation criteria based upon pattern recognition and clinical information. With optimal strategy, the rate of non-diagnostic findings is only about 1%. The sensitivity of CT is too low to exclude subsegmental PE,. The radiation dose is for CT is several times higher than for V/PSPECT. Quantification of PE, only offered by V/PSPECT has impact on therapy and is vital for follow up. Limited availability of V/PSPECT makes CT an essential element in a strategy for diagnosis of PE. The single breath test for CO2 offers an alternative when imaging techniques are not available or when radiation is a particular problem in early pregnancy.},
  author       = {Jonson, Björn and Bajc, Marika},
  issn         = {1747-1060},
  language     = {eng},
  number       = {4},
  pages        = {237--243},
  publisher    = {Informa Healthcare},
  series       = {Journal of Organ Dysfuntion},
  title        = {Diagnostics of pulmonary embolism with emphasis of ventilation/perfusion scintigraphy and dead space analysis},
  url          = {http://dx.doi.org/10.1080/17471060600580649},
  doi          = {10.1080/17471060600580649},
  volume       = {2},
  year         = {2006},
}