Improved survival rate for women with interval breast cancer - results from the breast cancer screening programme in Malmo, Sweden 1976-1999
(2007) In Journal of Medical Screening 14(3). p.138-143- Abstract
- OBJECTIVE: Breast cancers detected between screening examinations can influence the sensitivity of a screening programme. Studies of the prognosis of these so-called interval breast cancers show diverging results. We investigated the course of interval breast cancer over time in the Malmo Mammographic Screening Trial (MMST) 1976-86 and the Malmo Mammographic Service Screening Programme (MMSSP) 1990-99. MATERIAL AND METHODS: Stage distribution and survival of interval cancers in MMSSP were compared with screen-detected and non-attender cancer cases in MMSSP, with interval cancers in MMST and with breast cancer cases in a non-screened population five years before the start of MMSSP (pre-screening cancer cases). RESULTS: In MMSSP 1990-99, the... (More)
- OBJECTIVE: Breast cancers detected between screening examinations can influence the sensitivity of a screening programme. Studies of the prognosis of these so-called interval breast cancers show diverging results. We investigated the course of interval breast cancer over time in the Malmo Mammographic Screening Trial (MMST) 1976-86 and the Malmo Mammographic Service Screening Programme (MMSSP) 1990-99. MATERIAL AND METHODS: Stage distribution and survival of interval cancers in MMSSP were compared with screen-detected and non-attender cancer cases in MMSSP, with interval cancers in MMST and with breast cancer cases in a non-screened population five years before the start of MMSSP (pre-screening cancer cases). RESULTS: In MMSSP 1990-99, the interval cancers did not differ in stage distribution or survival compared with cancer cases in non-attenders, while screen-detected cancer cases had more favourable stage distribution and rate of survival than had the interval cancer cases. The MMST interval cancer cases, 1976-1986, had more favourable stage distribution but higher overall case fatality rate, relative risks (RR) 1.78 (1.00-3.20), and breast cancer case fatality rate, RR 2.05 (1.05-4.00), compared with the more recent MMSSP interval cancer cases. No significant difference in five-year survival was seen in the MMSSP interval cancer cases compared with pre-screening cancer cases not exposed to screening. CONCLUSION: In this urban population invited to mammographic screening, the survival rate for women with interval cancer has improved over a period of 20 years. Further studies are needed to assess what factors might explain changes in the course of interval breast cancer. (Less)
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https://lup.lub.lu.se/record/1137792
- author
- Zackrisson, Sophia LU ; Janzon, Lars LU ; Manjer, Jonas LU and Andersson, Ingvar LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Medical Screening
- volume
- 14
- issue
- 3
- pages
- 138 - 143
- publisher
- Royal Society of Medicine Press
- external identifiers
-
- pmid:17925086
- wos:000251002100006
- scopus:34848889948
- ISSN
- 1475-5793
- DOI
- 10.1258/096914107782066239
- language
- English
- LU publication?
- yes
- id
- ac0e13ea-a63e-4e37-9dc8-5bf1cda7733b (old id 1137792)
- date added to LUP
- 2016-04-04 09:42:11
- date last changed
- 2022-02-13 18:36:20
@article{ac0e13ea-a63e-4e37-9dc8-5bf1cda7733b,
abstract = {{OBJECTIVE: Breast cancers detected between screening examinations can influence the sensitivity of a screening programme. Studies of the prognosis of these so-called interval breast cancers show diverging results. We investigated the course of interval breast cancer over time in the Malmo Mammographic Screening Trial (MMST) 1976-86 and the Malmo Mammographic Service Screening Programme (MMSSP) 1990-99. MATERIAL AND METHODS: Stage distribution and survival of interval cancers in MMSSP were compared with screen-detected and non-attender cancer cases in MMSSP, with interval cancers in MMST and with breast cancer cases in a non-screened population five years before the start of MMSSP (pre-screening cancer cases). RESULTS: In MMSSP 1990-99, the interval cancers did not differ in stage distribution or survival compared with cancer cases in non-attenders, while screen-detected cancer cases had more favourable stage distribution and rate of survival than had the interval cancer cases. The MMST interval cancer cases, 1976-1986, had more favourable stage distribution but higher overall case fatality rate, relative risks (RR) 1.78 (1.00-3.20), and breast cancer case fatality rate, RR 2.05 (1.05-4.00), compared with the more recent MMSSP interval cancer cases. No significant difference in five-year survival was seen in the MMSSP interval cancer cases compared with pre-screening cancer cases not exposed to screening. CONCLUSION: In this urban population invited to mammographic screening, the survival rate for women with interval cancer has improved over a period of 20 years. Further studies are needed to assess what factors might explain changes in the course of interval breast cancer.}},
author = {{Zackrisson, Sophia and Janzon, Lars and Manjer, Jonas and Andersson, Ingvar}},
issn = {{1475-5793}},
language = {{eng}},
number = {{3}},
pages = {{138--143}},
publisher = {{Royal Society of Medicine Press}},
series = {{Journal of Medical Screening}},
title = {{Improved survival rate for women with interval breast cancer - results from the breast cancer screening programme in Malmo, Sweden 1976-1999}},
url = {{http://dx.doi.org/10.1258/096914107782066239}},
doi = {{10.1258/096914107782066239}},
volume = {{14}},
year = {{2007}},
}