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Surgery for metastatic lesions of the femur: Good outcome after 245 operations in 216 patients

Nilsson, Johan E LU and Gustafson, Pelle LU (2008) In Injury 39(4). p.404-410
Abstract
We report our experience with surgery for femoral metastatic lesions, based on 216 patients who underwent a total of 245 operations for femoral metastatic lesions. The median age was 66 (30-94) years, and the most common diagnosis breast cancer, followed by prostate cancer. All patients had pain on weight bearing, 196 had pain at rest, 147 were unable to walk preoperatively, and 148 were confined to a health-care facility. The patients were operated with bipolar hip prosthesis (n=7), total hip replacement (THR) with Harrington reconstruction of the acetabulum (n=42), ordinary THR (n=108), intramedullary nailing (n=55), and other techniques (n=33). All patients improved as regards pain at rest, pain on weight bearing, walking ability and... (More)
We report our experience with surgery for femoral metastatic lesions, based on 216 patients who underwent a total of 245 operations for femoral metastatic lesions. The median age was 66 (30-94) years, and the most common diagnosis breast cancer, followed by prostate cancer. All patients had pain on weight bearing, 196 had pain at rest, 147 were unable to walk preoperatively, and 148 were confined to a health-care facility. The patients were operated with bipolar hip prosthesis (n=7), total hip replacement (THR) with Harrington reconstruction of the acetabulum (n=42), ordinary THR (n=108), intramedullary nailing (n=55), and other techniques (n=33). All patients improved as regards pain at rest, pain on weight bearing, walking ability and social independence. The median survival for the 216 patients was 6 (0-123) months. All in all, 47 operations were followed by complications of any kind, where dislocations of hip prostheses and implant breakdown were the commonest, but pulmonary embolism the most serious. Patients with femoral metastatic lesions can be operated safely and with acceptable complication rates. Furthermore, large and long-standing gains as regards pain control and mobility can be expected. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Injury
volume
39
issue
4
pages
404 - 410
publisher
Elsevier
external identifiers
  • pmid:17996870
  • wos:000255223500004
  • scopus:40649126570
ISSN
1879-0267
DOI
10.1016/j.injury.2007.07.006
language
English
LU publication?
yes
id
e838eeec-293f-41d5-9077-a7aceb12294f (old id 1137858)
date added to LUP
2008-08-04 14:16:08
date last changed
2017-03-12 03:55:38
@article{e838eeec-293f-41d5-9077-a7aceb12294f,
  abstract     = {We report our experience with surgery for femoral metastatic lesions, based on 216 patients who underwent a total of 245 operations for femoral metastatic lesions. The median age was 66 (30-94) years, and the most common diagnosis breast cancer, followed by prostate cancer. All patients had pain on weight bearing, 196 had pain at rest, 147 were unable to walk preoperatively, and 148 were confined to a health-care facility. The patients were operated with bipolar hip prosthesis (n=7), total hip replacement (THR) with Harrington reconstruction of the acetabulum (n=42), ordinary THR (n=108), intramedullary nailing (n=55), and other techniques (n=33). All patients improved as regards pain at rest, pain on weight bearing, walking ability and social independence. The median survival for the 216 patients was 6 (0-123) months. All in all, 47 operations were followed by complications of any kind, where dislocations of hip prostheses and implant breakdown were the commonest, but pulmonary embolism the most serious. Patients with femoral metastatic lesions can be operated safely and with acceptable complication rates. Furthermore, large and long-standing gains as regards pain control and mobility can be expected.},
  author       = {Nilsson, Johan E and Gustafson, Pelle},
  issn         = {1879-0267},
  language     = {eng},
  number       = {4},
  pages        = {404--410},
  publisher    = {Elsevier},
  series       = {Injury},
  title        = {Surgery for metastatic lesions of the femur: Good outcome after 245 operations in 216 patients},
  url          = {http://dx.doi.org/10.1016/j.injury.2007.07.006},
  volume       = {39},
  year         = {2008},
}