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Development of comprehensive disease assessment in systemic vasculitis

Flossmann, Oliver; Bacon, Paul; de Groot, Kirsten; Jayne, David; Rasmussen, Niels; Seo, Philip; Westman, Kerstin LU and Luqmani, Raashid (2007) In Annals of the Rheumatic Diseases 66(3). p.283-292
Abstract
The systemic vasculitides are multisystem disorders with considerable mortality and morbidity and frequent relapses. In the absence of reliable serological markers, accurate clinical tools are required to assess disease activity and damage for treatment decisions, and for the performance of clinical trials. This article reviews and summarises the development and use of disease assessment tools for determining activity and damage in systemic vasculitis and reports ongoing initiatives for further development of disease assessment tools. A literature search was conducted using PubMed and reference lists for vasculitis, assessment, clinical trials, outcome and prognosis. The findings indicate that comprehensive disease assessment in vasculitis... (More)
The systemic vasculitides are multisystem disorders with considerable mortality and morbidity and frequent relapses. In the absence of reliable serological markers, accurate clinical tools are required to assess disease activity and damage for treatment decisions, and for the performance of clinical trials. This article reviews and summarises the development and use of disease assessment tools for determining activity and damage in systemic vasculitis and reports ongoing initiatives for further development of disease assessment tools. A literature search was conducted using PubMed and reference lists for vasculitis, assessment, clinical trials, outcome and prognosis. The findings indicate that comprehensive disease assessment in vasculitis requires documentation of disease activity, chronic irreversible damage and impairment of function. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Annals of the Rheumatic Diseases
volume
66
issue
3
pages
283 - 292
publisher
British Medical Association
external identifiers
  • pmid:16728460
  • scopus:34147224220
ISSN
1468-2060
DOI
10.1136/ard.2005.051078
language
English
LU publication?
yes
id
08918497-93ac-4a9e-9b9d-178e9dc32a57 (old id 1138505)
date added to LUP
2008-08-19 11:59:58
date last changed
2017-07-30 04:46:52
@article{08918497-93ac-4a9e-9b9d-178e9dc32a57,
  abstract     = {The systemic vasculitides are multisystem disorders with considerable mortality and morbidity and frequent relapses. In the absence of reliable serological markers, accurate clinical tools are required to assess disease activity and damage for treatment decisions, and for the performance of clinical trials. This article reviews and summarises the development and use of disease assessment tools for determining activity and damage in systemic vasculitis and reports ongoing initiatives for further development of disease assessment tools. A literature search was conducted using PubMed and reference lists for vasculitis, assessment, clinical trials, outcome and prognosis. The findings indicate that comprehensive disease assessment in vasculitis requires documentation of disease activity, chronic irreversible damage and impairment of function.},
  author       = {Flossmann, Oliver and Bacon, Paul and de Groot, Kirsten and Jayne, David and Rasmussen, Niels and Seo, Philip and Westman, Kerstin and Luqmani, Raashid},
  issn         = {1468-2060},
  language     = {eng},
  number       = {3},
  pages        = {283--292},
  publisher    = {British Medical Association},
  series       = {Annals of the Rheumatic Diseases},
  title        = {Development of comprehensive disease assessment in systemic vasculitis},
  url          = {http://dx.doi.org/10.1136/ard.2005.051078},
  volume       = {66},
  year         = {2007},
}