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Cardiovascular risk in the metabolic syndrome: fact or fiction?

Nilsson, Peter LU (2007) In Current Cardiology Reports 9(6). p.479-485
Abstract
In population-based studies, a cluster of cardiovascular risk factors comprising the metabolic syndrome (MetS) has been documented as predictive of cardiovascular disease events and type 2 diabetes. Currently, there are several proposed definitions of the MetS, although data support some advantages of using the 2005 National Cholesterol Education Program Adult Treatment Panel III definition, which is considered superior to most others, including the one from the 2005 International Diabetes Federation study. One controversial issue is that some of the conventional cardiovascular risk factors included in the MetS cluster appear to be equally predictive of cardiovascular outcomes as the syndrome itself (eg, the influence of smoking habits).... (More)
In population-based studies, a cluster of cardiovascular risk factors comprising the metabolic syndrome (MetS) has been documented as predictive of cardiovascular disease events and type 2 diabetes. Currently, there are several proposed definitions of the MetS, although data support some advantages of using the 2005 National Cholesterol Education Program Adult Treatment Panel III definition, which is considered superior to most others, including the one from the 2005 International Diabetes Federation study. One controversial issue is that some of the conventional cardiovascular risk factors included in the MetS cluster appear to be equally predictive of cardiovascular outcomes as the syndrome itself (eg, the influence of smoking habits). Further observational and intervention studies are needed to explore this issue and target the core problem of the syndrome, which is proposed to be insulin resistance. Useful therapies for the metabolic syndrome include lifestyle modification and drugs that lower conventional cardiovascular risk factors, such as metformin, the "glitazones," and evidence-based drugs. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Current Cardiology Reports
volume
9
issue
6
pages
479 - 485
publisher
Current Science
external identifiers
  • pmid:17999873
  • scopus:36049013606
ISSN
1534-3170
language
English
LU publication?
yes
id
63bf03fb-145e-473a-a20e-b6c9eade0431 (old id 1139688)
date added to LUP
2008-08-20 14:52:21
date last changed
2017-01-01 04:34:42
@article{63bf03fb-145e-473a-a20e-b6c9eade0431,
  abstract     = {In population-based studies, a cluster of cardiovascular risk factors comprising the metabolic syndrome (MetS) has been documented as predictive of cardiovascular disease events and type 2 diabetes. Currently, there are several proposed definitions of the MetS, although data support some advantages of using the 2005 National Cholesterol Education Program Adult Treatment Panel III definition, which is considered superior to most others, including the one from the 2005 International Diabetes Federation study. One controversial issue is that some of the conventional cardiovascular risk factors included in the MetS cluster appear to be equally predictive of cardiovascular outcomes as the syndrome itself (eg, the influence of smoking habits). Further observational and intervention studies are needed to explore this issue and target the core problem of the syndrome, which is proposed to be insulin resistance. Useful therapies for the metabolic syndrome include lifestyle modification and drugs that lower conventional cardiovascular risk factors, such as metformin, the "glitazones," and evidence-based drugs.},
  author       = {Nilsson, Peter},
  issn         = {1534-3170},
  language     = {eng},
  number       = {6},
  pages        = {479--485},
  publisher    = {Current Science},
  series       = {Current Cardiology Reports},
  title        = {Cardiovascular risk in the metabolic syndrome: fact or fiction?},
  volume       = {9},
  year         = {2007},
}