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Restorative cell therapy for Parkinson's disease: A quest for the perfect cell

Hall, Vanessa LU ; Li, Jia-Yi LU and Brundin, Patrik LU (2007) In Seminars in Cell & Developmental Biology 18(6). p.859-869
Abstract
The development of a cell therapy for the neurodegenerative disorder Parkinson's disease is a realistic ambition. It is pursued by researchers and companies alike, and spans different donor tissue types of embryonic, fetal and adult origins. In this review, we briefly outline the past and current status of research and clinical trials with cell transplantation in Parkinson's disease. We discuss studies on donor tissue derived from embryonic ventral mesencephalon and assess the current research on various forms of stem cells of both embryonic and adult origins in the quest to develop a cell-based therapy for this debilitating movement disorder.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Seminars in Cell & Developmental Biology
volume
18
issue
6
pages
859 - 869
publisher
Academic Press
external identifiers
  • pmid:17962052
  • wos:000253486700016
  • scopus:36249002320
ISSN
1084-9521
DOI
10.1016/j.semcdb.2007.09.004
language
English
LU publication?
yes
id
4fd73671-d1eb-45b6-a103-f356f7ec57d2 (old id 1139812)
date added to LUP
2008-07-28 14:18:34
date last changed
2017-10-22 04:31:13
@article{4fd73671-d1eb-45b6-a103-f356f7ec57d2,
  abstract     = {The development of a cell therapy for the neurodegenerative disorder Parkinson's disease is a realistic ambition. It is pursued by researchers and companies alike, and spans different donor tissue types of embryonic, fetal and adult origins. In this review, we briefly outline the past and current status of research and clinical trials with cell transplantation in Parkinson's disease. We discuss studies on donor tissue derived from embryonic ventral mesencephalon and assess the current research on various forms of stem cells of both embryonic and adult origins in the quest to develop a cell-based therapy for this debilitating movement disorder.},
  author       = {Hall, Vanessa and Li, Jia-Yi and Brundin, Patrik},
  issn         = {1084-9521},
  language     = {eng},
  number       = {6},
  pages        = {859--869},
  publisher    = {Academic Press},
  series       = {Seminars in Cell & Developmental Biology},
  title        = {Restorative cell therapy for Parkinson's disease: A quest for the perfect cell},
  url          = {http://dx.doi.org/10.1016/j.semcdb.2007.09.004},
  volume       = {18},
  year         = {2007},
}