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Sexual dysfunction and central obesity in patients with first episode psychosis

Theleritis, C; Bonaccorso, S; Habib, Naomi; Stahl, D; Gaughran, F; Vitoratou, S; Atakan, Z; Kolliakou, A; Gardner-Sood, P and Dazzan, P, et al. (2017) In European Psychiatry 42. p.1-7
Abstract

BACKGROUND: In recent years the association between sexual dysfunction (SD) and obesity in the general population has drawn major attention. Although sexual dysfunction is common in psychosis, its relationship with weight gain and obesity remains unclear.

AIMS: To investigate the association between sexual dysfunction and obesity in a cohort of patients with first episode psychosis.

METHOD: Sexual function was assessed in a cohort of patients with first episode psychosis using the Sexual Function Questionnaire (SFQ). Anthropometric measures, including weight, BMI, waist, waist-hip ratio were investigated. Additionally, leptin and testosterone were investigated in male patients.

RESULTS: A total of 116 patients (61... (More)

BACKGROUND: In recent years the association between sexual dysfunction (SD) and obesity in the general population has drawn major attention. Although sexual dysfunction is common in psychosis, its relationship with weight gain and obesity remains unclear.

AIMS: To investigate the association between sexual dysfunction and obesity in a cohort of patients with first episode psychosis.

METHOD: Sexual function was assessed in a cohort of patients with first episode psychosis using the Sexual Function Questionnaire (SFQ). Anthropometric measures, including weight, BMI, waist, waist-hip ratio were investigated. Additionally, leptin and testosterone were investigated in male patients.

RESULTS: A total of 116 patients (61 males and 55 females) were included. Of these 59% of males and 67.3% of females showed sexual dysfunction (SD) according to the SFQ. In males, higher SFQ scores were significantly correlated with higher BMI (Std. β=0.36, P=0.01), higher leptin levels (Std. β=0.34, P=0.02), higher waist-hip ratio (Std. β=0.32, P=0.04) and lower testosterone levels (Std. β=-0.44, P=0.002). In contrast, in females, SFQ scores were not associated with any of these factors.

CONCLUSIONS: While sexual dysfunction is present in both female and male patients with their first episode of psychosis, only in males is sexual dysfunction associated with increased BMI and waist-hip ratio. The association between SD, BMI, low levels of testosterone and high levels of leptin suggest that policies that lead to healthier diets and more active lifestyles can be beneficial at least, to male patients.

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published
keywords
Journal Article
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European Psychiatry
volume
42
pages
7 pages
publisher
Elsevier Masson SAS
external identifiers
  • scopus:85012048801
ISSN
1778-3585
DOI
10.1016/j.eurpsy.2016.11.008
language
English
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no
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113def5e-5ddc-4230-91e0-b91b182f2acb
date added to LUP
2017-08-06 13:34:52
date last changed
2018-01-07 12:14:09
@article{113def5e-5ddc-4230-91e0-b91b182f2acb,
  abstract     = {<p>BACKGROUND: In recent years the association between sexual dysfunction (SD) and obesity in the general population has drawn major attention. Although sexual dysfunction is common in psychosis, its relationship with weight gain and obesity remains unclear.</p><p>AIMS: To investigate the association between sexual dysfunction and obesity in a cohort of patients with first episode psychosis.</p><p>METHOD: Sexual function was assessed in a cohort of patients with first episode psychosis using the Sexual Function Questionnaire (SFQ). Anthropometric measures, including weight, BMI, waist, waist-hip ratio were investigated. Additionally, leptin and testosterone were investigated in male patients.</p><p>RESULTS: A total of 116 patients (61 males and 55 females) were included. Of these 59% of males and 67.3% of females showed sexual dysfunction (SD) according to the SFQ. In males, higher SFQ scores were significantly correlated with higher BMI (Std. β=0.36, P=0.01), higher leptin levels (Std. β=0.34, P=0.02), higher waist-hip ratio (Std. β=0.32, P=0.04) and lower testosterone levels (Std. β=-0.44, P=0.002). In contrast, in females, SFQ scores were not associated with any of these factors.</p><p>CONCLUSIONS: While sexual dysfunction is present in both female and male patients with their first episode of psychosis, only in males is sexual dysfunction associated with increased BMI and waist-hip ratio. The association between SD, BMI, low levels of testosterone and high levels of leptin suggest that policies that lead to healthier diets and more active lifestyles can be beneficial at least, to male patients.</p>},
  author       = {Theleritis, C and Bonaccorso, S and Habib, Naomi and Stahl, D and Gaughran, F and Vitoratou, S and Atakan, Z and Kolliakou, A and Gardner-Sood, P and Dazzan, P and Marques, T R and McGuire, P C and Greenwood, G. K. and Eberhard, J and Breedvelt, J and Ferracuti, S and Di Forti, M and Murray, R M and Smith, S},
  issn         = {1778-3585},
  keyword      = {Journal Article},
  language     = {eng},
  pages        = {1--7},
  publisher    = {Elsevier Masson SAS},
  series       = {European Psychiatry},
  title        = {Sexual dysfunction and central obesity in patients with first episode psychosis},
  url          = {http://dx.doi.org/10.1016/j.eurpsy.2016.11.008},
  volume       = {42},
  year         = {2017},
}