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Risk of developing diabetes is inversely related to lung function: a population-based cohort study.

Engström, Gunnar LU and Janzon, Lars LU (2002) In Diabetic Medicine 19(2). p.167-170
Abstract
AimTo investigate whether reduced lung function is a risk factor for developing diabetes.



MethodsNon-diabetic men (n = 382) from the population-based cohort 'Men Born in 1914' were examined with spirometry at age 55 years. The cohort was re-examined at 68 years. Diabetes and fasting plasma glucose at follow-up were studied in relation to vital capacity (VC) and forced expiratory volume (FEV1.0) at baseline.



ResultsFifteen men developed diabetes during the follow-up. The percentage with diabetes in the 1st, 2nd, 3rd and top quartile of vital capacity were 7%, 5%, 2%, and 1%, respectively (P for trend = 0.01). Fasting glucose (log transformed, mmol/l) at follow-up was 1.63 ± 0.16, 1.62 ± 0.18, 1.61 ±... (More)
AimTo investigate whether reduced lung function is a risk factor for developing diabetes.



MethodsNon-diabetic men (n = 382) from the population-based cohort 'Men Born in 1914' were examined with spirometry at age 55 years. The cohort was re-examined at 68 years. Diabetes and fasting plasma glucose at follow-up were studied in relation to vital capacity (VC) and forced expiratory volume (FEV1.0) at baseline.



ResultsFifteen men developed diabetes during the follow-up. The percentage with diabetes in the 1st, 2nd, 3rd and top quartile of vital capacity were 7%, 5%, 2%, and 1%, respectively (P for trend = 0.01). Fasting glucose (log transformed, mmol/l) at follow-up was 1.63 ± 0.16, 1.62 ± 0.18, 1.61 ± 0.11 and 1.60 ± 0.11, respectively (P for trend = 0.11). The longitudinal associations between VC and diabetes (P = 0.001) and log glucose (P = 0.036) were significant after adjustments for several potential confounders. FEV1.0 at baseline showed similar associations with diabetes at follow-up.



ConclusionsThe risk of developing diabetes is inversely associated with pulmonary function among middle-aged men. (Less)
Please use this url to cite or link to this publication:
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organization
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type
Contribution to journal
publication status
published
subject
keywords
Forced Expiratory Volume: physiology, Blood Glucose: metabolism, Blood Pressure, Body Mass Index, Cohort Studies, Diabetes Mellitus: epidemiology, Exercise, Human, Longitudinal Studies, Male, Middle Age, Respiratory Function Tests, Risk Factors, Smoking, Support, Non-U.S. Gov't, Sweden: epidemiology, Vital Capacity: physiology
in
Diabetic Medicine
volume
19
issue
2
pages
167 - 170
publisher
Wiley-Blackwell
external identifiers
  • wos:000174576300014
  • pmid:11874435
  • scopus:0036125054
ISSN
1464-5491
DOI
10.1046/j.1464-5491.2002.00652.x
language
English
LU publication?
yes
id
0e0d87f6-98cd-4d62-be85-3a2d97190156 (old id 115537)
date added to LUP
2007-07-18 14:40:11
date last changed
2017-08-06 04:37:50
@article{0e0d87f6-98cd-4d62-be85-3a2d97190156,
  abstract     = {AimTo investigate whether reduced lung function is a risk factor for developing diabetes.<br/><br>
<br/><br>
MethodsNon-diabetic men (n = 382) from the population-based cohort 'Men Born in 1914' were examined with spirometry at age 55 years. The cohort was re-examined at 68 years. Diabetes and fasting plasma glucose at follow-up were studied in relation to vital capacity (VC) and forced expiratory volume (FEV1.0) at baseline.<br/><br>
<br/><br>
ResultsFifteen men developed diabetes during the follow-up. The percentage with diabetes in the 1st, 2nd, 3rd and top quartile of vital capacity were 7%, 5%, 2%, and 1%, respectively (P for trend = 0.01). Fasting glucose (log transformed, mmol/l) at follow-up was 1.63 ± 0.16, 1.62 ± 0.18, 1.61 ± 0.11 and 1.60 ± 0.11, respectively (P for trend = 0.11). The longitudinal associations between VC and diabetes (P = 0.001) and log glucose (P = 0.036) were significant after adjustments for several potential confounders. FEV1.0 at baseline showed similar associations with diabetes at follow-up.<br/><br>
<br/><br>
ConclusionsThe risk of developing diabetes is inversely associated with pulmonary function among middle-aged men.},
  author       = {Engström, Gunnar and Janzon, Lars},
  issn         = {1464-5491},
  keyword      = {Forced Expiratory Volume: physiology,Blood Glucose: metabolism,Blood Pressure,Body Mass Index,Cohort Studies,Diabetes Mellitus: epidemiology,Exercise,Human,Longitudinal Studies,Male,Middle Age,Respiratory Function Tests,Risk Factors,Smoking,Support,Non-U.S. Gov't,Sweden: epidemiology,Vital Capacity: physiology},
  language     = {eng},
  number       = {2},
  pages        = {167--170},
  publisher    = {Wiley-Blackwell},
  series       = {Diabetic Medicine},
  title        = {Risk of developing diabetes is inversely related to lung function: a population-based cohort study.},
  url          = {http://dx.doi.org/10.1046/j.1464-5491.2002.00652.x},
  volume       = {19},
  year         = {2002},
}