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Breast tomosynthesis and digital mammography: a comparison of breast cancer visibility and BIRADS classification in a population of cancers with subtle mammographic findings.

Andersson, Ingvar LU ; Ikeda, Debra; Zackrisson, Sophia LU ; Ruschin, Mark LU ; Svahn, Tony LU ; Timberg, Pontus LU and Tingberg, Anders LU (2008) In European Radiology 18. p.2817-2825
Abstract
The main purpose was to compare breast cancer visibility in one-view breast tomosynthesis (BT) to cancer visibility in one- or two-view digital mammography (DM). Thirty-six patients were selected on the basis of subtle signs of breast cancer on DM. One-view BT was performed with the same compression angle as the DM image in which the finding was least/not visible. On BT, 25 projections images were acquired over an angular range of 50 degrees, with double the dose of one-view DM. Two expert breast imagers classified one- and two-view DM, and BT findings for cancer visibility and BIRADS cancer probability in a non-blinded consensus study. Forty breast cancers were found in 37 breasts. The cancers were rated more visible on BT compared to... (More)
The main purpose was to compare breast cancer visibility in one-view breast tomosynthesis (BT) to cancer visibility in one- or two-view digital mammography (DM). Thirty-six patients were selected on the basis of subtle signs of breast cancer on DM. One-view BT was performed with the same compression angle as the DM image in which the finding was least/not visible. On BT, 25 projections images were acquired over an angular range of 50 degrees, with double the dose of one-view DM. Two expert breast imagers classified one- and two-view DM, and BT findings for cancer visibility and BIRADS cancer probability in a non-blinded consensus study. Forty breast cancers were found in 37 breasts. The cancers were rated more visible on BT compared to one-view and two-view DM in 22 and 11 cases, respectively, (p < 0.01 for both comparisons). Comparing one-view DM to one-view BT, 21 patients were upgraded on BIRADS classification (p < 0.01). Comparing two-view DM to one-view BT, 12 patients were upgraded on BIRADS classification (p < 0.01). The results indicate that the cancer visibility on BT is superior to DM, which suggests that BT may have a higher sensitivity for breast cancer detection. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Radiology
volume
18
pages
2817 - 2825
publisher
Springer
external identifiers
  • wos:000260837300014
  • pmid:18641998
  • scopus:56349132626
ISSN
0938-7994
DOI
10.1007/s00330-008-1076-9
language
English
LU publication?
yes
id
6d5cc0de-a625-4ce8-8c25-538b070ff23d (old id 1180981)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18641998?dopt=Abstract
date added to LUP
2008-08-11 11:30:35
date last changed
2017-10-29 04:28:12
@article{6d5cc0de-a625-4ce8-8c25-538b070ff23d,
  abstract     = {The main purpose was to compare breast cancer visibility in one-view breast tomosynthesis (BT) to cancer visibility in one- or two-view digital mammography (DM). Thirty-six patients were selected on the basis of subtle signs of breast cancer on DM. One-view BT was performed with the same compression angle as the DM image in which the finding was least/not visible. On BT, 25 projections images were acquired over an angular range of 50 degrees, with double the dose of one-view DM. Two expert breast imagers classified one- and two-view DM, and BT findings for cancer visibility and BIRADS cancer probability in a non-blinded consensus study. Forty breast cancers were found in 37 breasts. The cancers were rated more visible on BT compared to one-view and two-view DM in 22 and 11 cases, respectively, (p &lt; 0.01 for both comparisons). Comparing one-view DM to one-view BT, 21 patients were upgraded on BIRADS classification (p &lt; 0.01). Comparing two-view DM to one-view BT, 12 patients were upgraded on BIRADS classification (p &lt; 0.01). The results indicate that the cancer visibility on BT is superior to DM, which suggests that BT may have a higher sensitivity for breast cancer detection.},
  author       = {Andersson, Ingvar and Ikeda, Debra and Zackrisson, Sophia and Ruschin, Mark and Svahn, Tony and Timberg, Pontus and Tingberg, Anders},
  issn         = {0938-7994},
  language     = {eng},
  pages        = {2817--2825},
  publisher    = {Springer},
  series       = {European Radiology},
  title        = {Breast tomosynthesis and digital mammography: a comparison of breast cancer visibility and BIRADS classification in a population of cancers with subtle mammographic findings.},
  url          = {http://dx.doi.org/10.1007/s00330-008-1076-9},
  volume       = {18},
  year         = {2008},
}