Increased plasma levels of ss(2)-microglobulin, cystatin C and ss-trace protein in term pregnancy are not due to utero-placental production.
Kristensen, Karl LU ; Strevens, Helena LU ; Lindström, Veronica LU
; Grubb, Anders
LU
and Wide-Swensson, Dag
LU
(2008)
In Scandinavian Journal of Clinical & Laboratory Investigation
68.
p.649-653
- Abstract
- Objective . To study concentration gradients of the low molecular mass proteins, ss(2)-microglobulin, cystatin C and ss-trace protein, between the uterine and ante-cubital veins, the umbilical artery and vein and in the amniotic fluid compartment. Material and methods. The study comprised 27 healthy women with uncomplicated pregnancies undergoing caesarean section at term. Samples were collected simultaneously and paired t-tests were used to compare mean plasma concentrations. Results . There was no significant concentration gradient in the plasma levels of ss(2)-microglobulin, cystatin C or ss-trace protein between the uterine and antecubital veins. There were no correlations between the protein levels in the compartments. Conclusion .... (More)
- Objective . To study concentration gradients of the low molecular mass proteins, ss(2)-microglobulin, cystatin C and ss-trace protein, between the uterine and ante-cubital veins, the umbilical artery and vein and in the amniotic fluid compartment. Material and methods. The study comprised 27 healthy women with uncomplicated pregnancies undergoing caesarean section at term. Samples were collected simultaneously and paired t-tests were used to compare mean plasma concentrations. Results . There was no significant concentration gradient in the plasma levels of ss(2)-microglobulin, cystatin C or ss-trace protein between the uterine and antecubital veins. There were no correlations between the protein levels in the compartments. Conclusion . The utero-placental unit does not contribute significantly to the maternal levels of ss(2)-microglobulin, cystatin C and ss-trace protein in normal pregnancy, and the proteins are not likely to be transferred across the placental barrier. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1181397
- author
- Kristensen, Karl
LU
; Strevens, Helena
LU
; Lindström, Veronica
LU
; Grubb, Anders
LU
and Wide-Swensson, Dag
LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scandinavian Journal of Clinical & Laboratory Investigation
- volume
- 68
- pages
- 649 - 653
- publisher
- Informa Healthcare
- external identifiers
-
- wos:000260497100020
- pmid:18609110
- scopus:55249105258
- ISSN
- 1502-7686
- DOI
- 10.1080/00365510802007804
- language
- English
- LU publication?
- yes
- id
- f90b8537-4ece-4387-b4ac-a3c2371c7732 (old id 1181397)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/18609110?dopt=Abstract
- date added to LUP
- 2016-04-04 09:14:48
- date last changed
- 2023-01-05 18:53:17
@article{f90b8537-4ece-4387-b4ac-a3c2371c7732,
abstract = {{Objective . To study concentration gradients of the low molecular mass proteins, ss(2)-microglobulin, cystatin C and ss-trace protein, between the uterine and ante-cubital veins, the umbilical artery and vein and in the amniotic fluid compartment. Material and methods. The study comprised 27 healthy women with uncomplicated pregnancies undergoing caesarean section at term. Samples were collected simultaneously and paired t-tests were used to compare mean plasma concentrations. Results . There was no significant concentration gradient in the plasma levels of ss(2)-microglobulin, cystatin C or ss-trace protein between the uterine and antecubital veins. There were no correlations between the protein levels in the compartments. Conclusion . The utero-placental unit does not contribute significantly to the maternal levels of ss(2)-microglobulin, cystatin C and ss-trace protein in normal pregnancy, and the proteins are not likely to be transferred across the placental barrier.}},
author = {{Kristensen, Karl and Strevens, Helena and Lindström, Veronica and Grubb, Anders and Wide-Swensson, Dag}},
issn = {{1502-7686}},
language = {{eng}},
pages = {{649--653}},
publisher = {{Informa Healthcare}},
series = {{Scandinavian Journal of Clinical & Laboratory Investigation}},
title = {{Increased plasma levels of ss(2)-microglobulin, cystatin C and ss-trace protein in term pregnancy are not due to utero-placental production.}},
url = {{http://dx.doi.org/10.1080/00365510802007804}},
doi = {{10.1080/00365510802007804}},
volume = {{68}},
year = {{2008}},
}