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Abdominal aortic aneurysm and cytomegalovirus infection

Nyberg, Anders; Skagius, Elisabet; Nilsson, Ingrid LU ; Ljungh, Åsa LU and Henriksson, Anders E (2008) In Journal of Medical Virology 80(4). p.667-669
Abstract
Cytomegalovirus (CMV) has been implicated in the pathogenesis of atherosclerosis. Abdominal aortic aneurysm is regarded traditionally as a consequence of atherosclerosis. Several microorganisms have been suggested as possible contributing factors for the development of abdominal aortic aneurysm. The relevance of CMV in the processes underlying the development, expansion, and rupture of abdominal aortic aneurysm is unknown. The aim of the present study was to investigate whether CMV infection is related to abdominal aortic aneurysm rupture. One hundred nineteen patients with abdominal aortic aneurysm and 36 matched controls without abdominal aortic aneurysm were investigated prospectively by CMV serology. Patients with ruptured abdominal... (More)
Cytomegalovirus (CMV) has been implicated in the pathogenesis of atherosclerosis. Abdominal aortic aneurysm is regarded traditionally as a consequence of atherosclerosis. Several microorganisms have been suggested as possible contributing factors for the development of abdominal aortic aneurysm. The relevance of CMV in the processes underlying the development, expansion, and rupture of abdominal aortic aneurysm is unknown. The aim of the present study was to investigate whether CMV infection is related to abdominal aortic aneurysm rupture. One hundred nineteen patients with abdominal aortic aneurysm and 36 matched controls without abdominal aortic aneurysm were investigated prospectively by CMV serology. Patients with ruptured abdominal aortic aneurysm have similar levels of IgG antibodies against CMV as patients with nonruptured abdominal aortic aneurysm, small abdominal aortic aneurysm, and controls without abdominal aortic aneurysm. In conclusion, this study fails to demonstrate a connection between CMV infection and abdominal aortic aneurysm rupture. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
cytomegalovirus, aortic aneurysm, rupture
in
Journal of Medical Virology
volume
80
issue
4
pages
667 - 669
publisher
John Wiley & Sons
external identifiers
  • wos:000253789800015
  • scopus:40549099376
ISSN
1096-9071
DOI
10.1002/jmv.21022
language
English
LU publication?
yes
id
0ae77172-e49f-4997-a156-865a8ccd5bbe (old id 1185976)
date added to LUP
2008-09-03 11:48:27
date last changed
2017-01-01 05:01:08
@article{0ae77172-e49f-4997-a156-865a8ccd5bbe,
  abstract     = {Cytomegalovirus (CMV) has been implicated in the pathogenesis of atherosclerosis. Abdominal aortic aneurysm is regarded traditionally as a consequence of atherosclerosis. Several microorganisms have been suggested as possible contributing factors for the development of abdominal aortic aneurysm. The relevance of CMV in the processes underlying the development, expansion, and rupture of abdominal aortic aneurysm is unknown. The aim of the present study was to investigate whether CMV infection is related to abdominal aortic aneurysm rupture. One hundred nineteen patients with abdominal aortic aneurysm and 36 matched controls without abdominal aortic aneurysm were investigated prospectively by CMV serology. Patients with ruptured abdominal aortic aneurysm have similar levels of IgG antibodies against CMV as patients with nonruptured abdominal aortic aneurysm, small abdominal aortic aneurysm, and controls without abdominal aortic aneurysm. In conclusion, this study fails to demonstrate a connection between CMV infection and abdominal aortic aneurysm rupture.},
  author       = {Nyberg, Anders and Skagius, Elisabet and Nilsson, Ingrid and Ljungh, Åsa and Henriksson, Anders E},
  issn         = {1096-9071},
  keyword      = {cytomegalovirus,aortic aneurysm,rupture},
  language     = {eng},
  number       = {4},
  pages        = {667--669},
  publisher    = {John Wiley & Sons},
  series       = {Journal of Medical Virology},
  title        = {Abdominal aortic aneurysm and cytomegalovirus infection},
  url          = {http://dx.doi.org/10.1002/jmv.21022},
  volume       = {80},
  year         = {2008},
}