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Prophylaxis and treatment of HIV-1 infection in pregnancy: Swedish recommendations 2007

Naver, Lars; Bohlin, Ann-Britt; Albert, Jan; Flamholc, Leo LU ; Gisslen, Magnus; Gyllensten, Katarina; Josephson, Filip; Pehrson, Pehrolov; Sonnerborg, Anders and Westling, Katarina, et al. (2008) In Scandinavian Journal of Infectious Diseases 40(6-7). p.451-461
Abstract
Prophylaxis and treatment with antiretroviral drugs, a consequent low viral load, and the use of elective Caesarean section, are factors that radically decrease the risk of HIV transmission from mother to child during pregnancy and delivery. The availability of new antiretroviral drugs, updated general treatment guidelines and increasing knowledge of the importance of drug resistance, have necessitated recurrent revisions of the recommendations for 'Prophylaxis and treatment of HIV-1 infection in pregnancy'. For these reasons, The Swedish Reference Group for Antiviral Therapy (RAV) has, at an expert meeting on May 4, 2007, once more updated the treatment recommendations of 1999, 2002 and 2005, which were defined in cooperation with the... (More)
Prophylaxis and treatment with antiretroviral drugs, a consequent low viral load, and the use of elective Caesarean section, are factors that radically decrease the risk of HIV transmission from mother to child during pregnancy and delivery. The availability of new antiretroviral drugs, updated general treatment guidelines and increasing knowledge of the importance of drug resistance, have necessitated recurrent revisions of the recommendations for 'Prophylaxis and treatment of HIV-1 infection in pregnancy'. For these reasons, The Swedish Reference Group for Antiviral Therapy (RAV) has, at an expert meeting on May 4, 2007, once more updated the treatment recommendations of 1999, 2002 and 2005, which were defined in cooperation with the Swedish Medical Products Agency (Lakemedelsverket). This new text takes the recently updated general HIV treatment recommendations into account. Furthermore, the very low risk of HIV transmission when the mother is treated with combination antiretroviral therapy, has undetectable levels of viraemia and no obstetric risk factors, has been considered in the recommendations concerning the mode of delivery. Finally, the recommendations for monitoring of infants born to HIV-infected mothers have been modified. The recommendations are evidence graded in accordance with the Oxford Centre for Evidence Based Medicine, 2001 (see http://www.cebm.net/levels_of_evidence.asp#levels). (Less)
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published
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in
Scandinavian Journal of Infectious Diseases
volume
40
issue
6-7
pages
451 - 461
publisher
Informa Healthcare
external identifiers
  • wos:000257148100002
  • scopus:47349104088
ISSN
1651-1980
DOI
10.1080/00365540801894787
language
English
LU publication?
yes
id
6fb6d970-30af-4736-ba8d-d099200a0874 (old id 1186323)
date added to LUP
2008-09-03 14:43:37
date last changed
2017-01-01 06:19:55
@article{6fb6d970-30af-4736-ba8d-d099200a0874,
  abstract     = {Prophylaxis and treatment with antiretroviral drugs, a consequent low viral load, and the use of elective Caesarean section, are factors that radically decrease the risk of HIV transmission from mother to child during pregnancy and delivery. The availability of new antiretroviral drugs, updated general treatment guidelines and increasing knowledge of the importance of drug resistance, have necessitated recurrent revisions of the recommendations for 'Prophylaxis and treatment of HIV-1 infection in pregnancy'. For these reasons, The Swedish Reference Group for Antiviral Therapy (RAV) has, at an expert meeting on May 4, 2007, once more updated the treatment recommendations of 1999, 2002 and 2005, which were defined in cooperation with the Swedish Medical Products Agency (Lakemedelsverket). This new text takes the recently updated general HIV treatment recommendations into account. Furthermore, the very low risk of HIV transmission when the mother is treated with combination antiretroviral therapy, has undetectable levels of viraemia and no obstetric risk factors, has been considered in the recommendations concerning the mode of delivery. Finally, the recommendations for monitoring of infants born to HIV-infected mothers have been modified. The recommendations are evidence graded in accordance with the Oxford Centre for Evidence Based Medicine, 2001 (see http://www.cebm.net/levels_of_evidence.asp#levels).},
  author       = {Naver, Lars and Bohlin, Ann-Britt and Albert, Jan and Flamholc, Leo and Gisslen, Magnus and Gyllensten, Katarina and Josephson, Filip and Pehrson, Pehrolov and Sonnerborg, Anders and Westling, Katarina and Lindgren, Susanne},
  issn         = {1651-1980},
  language     = {eng},
  number       = {6-7},
  pages        = {451--461},
  publisher    = {Informa Healthcare},
  series       = {Scandinavian Journal of Infectious Diseases},
  title        = {Prophylaxis and treatment of HIV-1 infection in pregnancy: Swedish recommendations 2007},
  url          = {http://dx.doi.org/10.1080/00365540801894787},
  volume       = {40},
  year         = {2008},
}