Comparison of two strategies to reduce ventricular pacing in pacemaker patients
(2008) In PACE 31(2). p.167-176- Abstract
- Background: Managed Ventricular Pacing (MVP) and Search AV+ (SAV+) are two pacing algorithms designed to reduce ventricular pacing, MVP promotes conduction by operating in AAI/R mode with backup ventricular pacing during atrioventricular block (AVB). SAV+ operates in DDD/R mode with a nominal AV extension of 290 ms during atrial sensing and 320 ms during atrial pacing. The reduction in ventricular pacing was compared with these two algorithms in pacemaker patients. Methods: The EnRhythm and EnPulse clinical studies assessed the Percentage of ventricular pacing (% VP) after 1 month. Each patient's AVB status was assigned using the following hierarchical categories: persistent third-degree AVB (p3AVB), episodic third-degree AVB (e3AVB),... (More)
- Background: Managed Ventricular Pacing (MVP) and Search AV+ (SAV+) are two pacing algorithms designed to reduce ventricular pacing, MVP promotes conduction by operating in AAI/R mode with backup ventricular pacing during atrioventricular block (AVB). SAV+ operates in DDD/R mode with a nominal AV extension of 290 ms during atrial sensing and 320 ms during atrial pacing. The reduction in ventricular pacing was compared with these two algorithms in pacemaker patients. Methods: The EnRhythm and EnPulse clinical studies assessed the Percentage of ventricular pacing (% VP) after 1 month. Each patient's AVB status was assigned using the following hierarchical categories: persistent third-degree AVB (p3AVB), episodic third-degree AVB (e3AVB), second-degree AVB (2AVB), first-degree AVB (1AVB), and no AVB (nAVB). The% VP was tabulated for each AVB status category. Results: Data were available from 322 patients of whom 129 received DDD(R) pacing with the MVP algorithm activated and 193 patients with DDD(R) pacing and the SAV+ function activated, each for a month period. MVP resulted in a significantly lower median % VP than SAV+ in all AVB categories except for p3AVB: nAVB (0.3 vs 2.9, P < 0.0001), 1AVB (0.9% vs 80.6%. P < 0.0001), 2AVB (37.6 vs 99.3. P < 0.002), e3AVB (1.2 vs 42.2, P = 0.02), p3AVB (98.9 vs 100, P = 1.00). Conclusion: MVP resulted in a greater reduction in% VP than SAV+ across all patient groups except persistent third-degree AV block. The greatest reduction in%VP was observed in patients with mildly impaired AV conduction. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1192782
- author
- Puererfellner, Helmut ; Brandt, Johan LU ; Israel, Carsten ; Sheldon, Todd ; Johnson, James ; Tscheliessnigg, Karlheinz ; Sperzel, Johannes ; Boriani, Giuseppe ; Puglisi, Andrea and Milasinovic, Goran
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- intrinsic AV conduction, ventricular pacing, AV block, pacing algorithms
- in
- PACE
- volume
- 31
- issue
- 2
- pages
- 167 - 176
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000253676000006
- scopus:38849110690
- pmid:18233969
- ISSN
- 1540-8159
- DOI
- 10.1111/j.1540-8159.2007.00965.x
- language
- English
- LU publication?
- yes
- id
- 3b1b4b82-7782-40fa-9526-84751dad02ac (old id 1192782)
- date added to LUP
- 2016-04-01 15:01:21
- date last changed
- 2022-01-28 03:43:04
@article{3b1b4b82-7782-40fa-9526-84751dad02ac, abstract = {{Background: Managed Ventricular Pacing (MVP) and Search AV+ (SAV+) are two pacing algorithms designed to reduce ventricular pacing, MVP promotes conduction by operating in AAI/R mode with backup ventricular pacing during atrioventricular block (AVB). SAV+ operates in DDD/R mode with a nominal AV extension of 290 ms during atrial sensing and 320 ms during atrial pacing. The reduction in ventricular pacing was compared with these two algorithms in pacemaker patients. Methods: The EnRhythm and EnPulse clinical studies assessed the Percentage of ventricular pacing (% VP) after 1 month. Each patient's AVB status was assigned using the following hierarchical categories: persistent third-degree AVB (p3AVB), episodic third-degree AVB (e3AVB), second-degree AVB (2AVB), first-degree AVB (1AVB), and no AVB (nAVB). The% VP was tabulated for each AVB status category. Results: Data were available from 322 patients of whom 129 received DDD(R) pacing with the MVP algorithm activated and 193 patients with DDD(R) pacing and the SAV+ function activated, each for a month period. MVP resulted in a significantly lower median % VP than SAV+ in all AVB categories except for p3AVB: nAVB (0.3 vs 2.9, P < 0.0001), 1AVB (0.9% vs 80.6%. P < 0.0001), 2AVB (37.6 vs 99.3. P < 0.002), e3AVB (1.2 vs 42.2, P = 0.02), p3AVB (98.9 vs 100, P = 1.00). Conclusion: MVP resulted in a greater reduction in% VP than SAV+ across all patient groups except persistent third-degree AV block. The greatest reduction in%VP was observed in patients with mildly impaired AV conduction.}}, author = {{Puererfellner, Helmut and Brandt, Johan and Israel, Carsten and Sheldon, Todd and Johnson, James and Tscheliessnigg, Karlheinz and Sperzel, Johannes and Boriani, Giuseppe and Puglisi, Andrea and Milasinovic, Goran}}, issn = {{1540-8159}}, keywords = {{intrinsic AV conduction; ventricular pacing; AV block; pacing algorithms}}, language = {{eng}}, number = {{2}}, pages = {{167--176}}, publisher = {{Wiley-Blackwell}}, series = {{PACE}}, title = {{Comparison of two strategies to reduce ventricular pacing in pacemaker patients}}, url = {{http://dx.doi.org/10.1111/j.1540-8159.2007.00965.x}}, doi = {{10.1111/j.1540-8159.2007.00965.x}}, volume = {{31}}, year = {{2008}}, }