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Intranasal Immunization of Mice with Group B Streptococcal Protein Rib and Cholera Toxin B Subunit Confers Protection against Lethal Infection.

Larsson, Charlotte U LU ; Holmgren, Jan; Lindahl, Gunnar LU and Bergquist, Charlotta (2004) In Infection and Immunity 72(2). p.1184-1187
Abstract
Intranasal immunization of mice with Rib, a cell surface protein of group B streptococcus (GBS), conjugated to or simply coadministered with the recombinant cholera toxin B subunit, induces systemic immunoglobulin G (IgG) and local IgA antibody responses and confers protection against lethal GBS infection. These findings have implications for the development of a human GBS vaccine.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Infection and Immunity
volume
72
issue
2
pages
1184 - 1187
publisher
American Society for Microbiology
external identifiers
  • pmid:14742572
  • wos:000188766400072
  • scopus:0842282992
ISSN
1098-5522
DOI
10.1128/IAI.72.2.1184-1187.2004
language
English
LU publication?
yes
id
f2d86322-1ee9-4c99-9f28-1fadb3baf008 (old id 119962)
date added to LUP
2007-07-10 07:36:37
date last changed
2017-02-26 03:26:59
@article{f2d86322-1ee9-4c99-9f28-1fadb3baf008,
  abstract     = {Intranasal immunization of mice with Rib, a cell surface protein of group B streptococcus (GBS), conjugated to or simply coadministered with the recombinant cholera toxin B subunit, induces systemic immunoglobulin G (IgG) and local IgA antibody responses and confers protection against lethal GBS infection. These findings have implications for the development of a human GBS vaccine.},
  author       = {Larsson, Charlotte U and Holmgren, Jan and Lindahl, Gunnar and Bergquist, Charlotta},
  issn         = {1098-5522},
  language     = {eng},
  number       = {2},
  pages        = {1184--1187},
  publisher    = {American Society for Microbiology},
  series       = {Infection and Immunity},
  title        = {Intranasal Immunization of Mice with Group B Streptococcal Protein Rib and Cholera Toxin B Subunit Confers Protection against Lethal Infection.},
  url          = {http://dx.doi.org/10.1128/IAI.72.2.1184-1187.2004},
  volume       = {72},
  year         = {2004},
}