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Artificial receptors

Danielsson, Bengt LU (2008) In Biosensing for the 21st Century (Advances in Biochemical Engineering/Biotechnology) 109. p.97-122
Abstract
Herein I will provide a brief overview of artificial receptors with emphasis on molecularly imprinted polymers (MIPs) and their applications. Alternative techniques to produce artificial receptors such as in silico designed and modelled polymers as well as different receptors designed using libraries of more or less natural composition will also be mentioned. Examples of these include aptamers and bio-nanocomposites. The physical presentation of the receptors is important and may depend on the application. Block polymerization of MIPs and grinding to particles of suitable size used to be the preferred technique, but today beaded materials can be produced in sizes down to nanobeads and also nanofibers can be used to increase available... (More)
Herein I will provide a brief overview of artificial receptors with emphasis on molecularly imprinted polymers (MIPs) and their applications. Alternative techniques to produce artificial receptors such as in silico designed and modelled polymers as well as different receptors designed using libraries of more or less natural composition will also be mentioned. Examples of these include aptamers and bio-nanocomposites. The physical presentation of the receptors is important and may depend on the application. Block polymerization of MIPs and grinding to particles of suitable size used to be the preferred technique, but today beaded materials can be produced in sizes down to nanobeads and also nanofibers can be used to increase available surface area and thereby capacity. For sensor applications it may be attractive to include the artificial receptors in surface coatings or in membrane structures. Different composite designs can be used to provide additional desirable properties. MIPs and other artificial receptors are gaining rapidly increasing attention in very shifting application areas and an attempt to provide a systematic account for current applications has been made with examples from separation, solid-phase extraction, analysis, carbohydrate specific experiments, and MIPs-directed synthesis. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
ion channel sensors, aptamers, combinatorial libraries, MIP catalysis, MIPs, solid-phase extraction, molecularly imprinted polymers
in
Biosensing for the 21st Century (Advances in Biochemical Engineering/Biotechnology)
volume
109
pages
97 - 122
publisher
Springer
external identifiers
  • wos:000252396500004
  • scopus:36749053434
ISSN
0724-6145
ISBN
978-3-540-75200-4
DOI
10.1007/10_2007_088
language
English
LU publication?
yes
id
b32fde35-7cfa-4338-8b81-8fd0a57ac57b (old id 1199987)
date added to LUP
2008-09-11 14:24:17
date last changed
2017-08-20 04:07:14
@inbook{b32fde35-7cfa-4338-8b81-8fd0a57ac57b,
  abstract     = {Herein I will provide a brief overview of artificial receptors with emphasis on molecularly imprinted polymers (MIPs) and their applications. Alternative techniques to produce artificial receptors such as in silico designed and modelled polymers as well as different receptors designed using libraries of more or less natural composition will also be mentioned. Examples of these include aptamers and bio-nanocomposites. The physical presentation of the receptors is important and may depend on the application. Block polymerization of MIPs and grinding to particles of suitable size used to be the preferred technique, but today beaded materials can be produced in sizes down to nanobeads and also nanofibers can be used to increase available surface area and thereby capacity. For sensor applications it may be attractive to include the artificial receptors in surface coatings or in membrane structures. Different composite designs can be used to provide additional desirable properties. MIPs and other artificial receptors are gaining rapidly increasing attention in very shifting application areas and an attempt to provide a systematic account for current applications has been made with examples from separation, solid-phase extraction, analysis, carbohydrate specific experiments, and MIPs-directed synthesis.},
  author       = {Danielsson, Bengt},
  isbn         = {978-3-540-75200-4},
  issn         = {0724-6145},
  keyword      = {ion channel sensors,aptamers,combinatorial libraries,MIP catalysis,MIPs,solid-phase extraction,molecularly imprinted polymers},
  language     = {eng},
  pages        = {97--122},
  publisher    = {Springer},
  series       = {Biosensing for the 21st Century (Advances in Biochemical Engineering/Biotechnology)},
  title        = {Artificial receptors},
  url          = {http://dx.doi.org/10.1007/10_2007_088},
  volume       = {109},
  year         = {2008},
}