Single hollow fiber SLM extraction of polyamines followed by tosyl chloride derivatization and HPLC determination
(2008) In Analytica Chimica Acta 606(2). p.184-193- Abstract
- Determination of polyamines in biological fluids possesses medical diagnostic relevance. Despite the vast panel of analytical methods developed for polyamines they are not applied in routine clinical usage, mainly due to the time and labor consuming sample preparation step and complicated derivatization. procedures. Thus, new simpler methods are needed. This paper describes a single hollow fiber SLM extraction method of polyarnines followed by simple pre-column derivatization with tosyl chloride and HPLC-UV analysis. The influence of different parameters such as the extraction time, organic phase composition, acceptor pH, donor pH, acceptor volume, donor volume and stirring speed on the transport parameters and enrichment was studied and... (More)
- Determination of polyamines in biological fluids possesses medical diagnostic relevance. Despite the vast panel of analytical methods developed for polyamines they are not applied in routine clinical usage, mainly due to the time and labor consuming sample preparation step and complicated derivatization. procedures. Thus, new simpler methods are needed. This paper describes a single hollow fiber SLM extraction method of polyarnines followed by simple pre-column derivatization with tosyl chloride and HPLC-UV analysis. The influence of different parameters such as the extraction time, organic phase composition, acceptor pH, donor pH, acceptor volume, donor volume and stirring speed on the transport parameters and enrichment was studied and discussed. The optimized method was applied to real matrices such as urine and plasma. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1199997
- author
- Dziarkowska, Katarzyna ; Jönsson, Jan Åke LU and Wieczorek, Piotr P
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- polyamines, extraction technique, hollow fiber membrane, supported liquid membrane
- in
- Analytica Chimica Acta
- volume
- 606
- issue
- 2
- pages
- 184 - 193
- publisher
- Elsevier
- external identifiers
-
- wos:000252512300006
- scopus:37049023407
- pmid:18082649
- ISSN
- 1873-4324
- DOI
- 10.1016/j.aca.2007.11.014
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Analytical Chemistry (S/LTH) (011001004)
- id
- 6ce4059f-a779-4c8f-951e-b0afcf9f1a61 (old id 1199997)
- date added to LUP
- 2016-04-01 14:35:25
- date last changed
- 2022-01-28 01:24:58
@article{6ce4059f-a779-4c8f-951e-b0afcf9f1a61,
abstract = {{Determination of polyamines in biological fluids possesses medical diagnostic relevance. Despite the vast panel of analytical methods developed for polyamines they are not applied in routine clinical usage, mainly due to the time and labor consuming sample preparation step and complicated derivatization. procedures. Thus, new simpler methods are needed. This paper describes a single hollow fiber SLM extraction method of polyarnines followed by simple pre-column derivatization with tosyl chloride and HPLC-UV analysis. The influence of different parameters such as the extraction time, organic phase composition, acceptor pH, donor pH, acceptor volume, donor volume and stirring speed on the transport parameters and enrichment was studied and discussed. The optimized method was applied to real matrices such as urine and plasma.}},
author = {{Dziarkowska, Katarzyna and Jönsson, Jan Åke and Wieczorek, Piotr P}},
issn = {{1873-4324}},
keywords = {{polyamines; extraction technique; hollow fiber membrane; supported liquid membrane}},
language = {{eng}},
number = {{2}},
pages = {{184--193}},
publisher = {{Elsevier}},
series = {{Analytica Chimica Acta}},
title = {{Single hollow fiber SLM extraction of polyamines followed by tosyl chloride derivatization and HPLC determination}},
url = {{http://dx.doi.org/10.1016/j.aca.2007.11.014}},
doi = {{10.1016/j.aca.2007.11.014}},
volume = {{606}},
year = {{2008}},
}