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Increased sporulation rate of epidemic clostridium difficile type 027/NAP1

Åkerlund, Thomas; Persson, Ingela; Unemo, Magnus; Noren, Torbjörn; Svenungsson, Bo; Wullt, Marlene LU and Burman, Lars G (2008) In Journal of Clinical Microbiology 46(4). p.1530-1533
Abstract
Clostridium difficile PCR ribotype 027 comprised 0.2% of a collection of Swedish isolates in 1997-2001 (3 of 1,325 isolates). These isolates had lower moxifloxacin MICs than the epidemic type 027 isolates, but they had the same tcdC sequence and toxin yield. Type 027 produced 3- to 13-fold more toxin than did major Swedish types. One epidemic strain (027/NAP1a) sporulated more than did other type 027 isolates, a feature that should contribute to its survival and spread.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Clinical Microbiology
volume
46
issue
4
pages
1530 - 1533
publisher
American Society for Microbiology
external identifiers
  • wos:000254866400062
  • scopus:42449157632
  • pmid:18287318
ISSN
1098-660X
DOI
10.1128/JCM.01964-07
language
English
LU publication?
yes
id
13146aba-da50-4304-bbdf-eb05d5e1f8f9 (old id 1206367)
date added to LUP
2008-09-19 12:48:30
date last changed
2017-09-10 04:04:37
@article{13146aba-da50-4304-bbdf-eb05d5e1f8f9,
  abstract     = {Clostridium difficile PCR ribotype 027 comprised 0.2% of a collection of Swedish isolates in 1997-2001 (3 of 1,325 isolates). These isolates had lower moxifloxacin MICs than the epidemic type 027 isolates, but they had the same tcdC sequence and toxin yield. Type 027 produced 3- to 13-fold more toxin than did major Swedish types. One epidemic strain (027/NAP1a) sporulated more than did other type 027 isolates, a feature that should contribute to its survival and spread.},
  author       = {Åkerlund, Thomas and Persson, Ingela and Unemo, Magnus and Noren, Torbjörn and Svenungsson, Bo and Wullt, Marlene and Burman, Lars G},
  issn         = {1098-660X},
  language     = {eng},
  number       = {4},
  pages        = {1530--1533},
  publisher    = {American Society for Microbiology},
  series       = {Journal of Clinical Microbiology},
  title        = {Increased sporulation rate of epidemic clostridium difficile type 027/NAP1},
  url          = {http://dx.doi.org/10.1128/JCM.01964-07},
  volume       = {46},
  year         = {2008},
}