Increased sporulation rate of epidemic clostridium difficile type 027/NAP1
(2008) In Journal of Clinical Microbiology 46(4). p.1530-1533- Abstract
- Clostridium difficile PCR ribotype 027 comprised 0.2% of a collection of Swedish isolates in 1997-2001 (3 of 1,325 isolates). These isolates had lower moxifloxacin MICs than the epidemic type 027 isolates, but they had the same tcdC sequence and toxin yield. Type 027 produced 3- to 13-fold more toxin than did major Swedish types. One epidemic strain (027/NAP1a) sporulated more than did other type 027 isolates, a feature that should contribute to its survival and spread.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1206367
- author
- Åkerlund, Thomas ; Persson, Ingela ; Unemo, Magnus ; Noren, Torbjörn ; Svenungsson, Bo ; Wullt, Marlene LU and Burman, Lars G
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Clinical Microbiology
- volume
- 46
- issue
- 4
- pages
- 1530 - 1533
- publisher
- American Society for Microbiology
- external identifiers
-
- wos:000254866400062
- scopus:42449157632
- pmid:18287318
- pmid:18287318
- ISSN
- 1098-660X
- DOI
- 10.1128/JCM.01964-07
- language
- English
- LU publication?
- yes
- id
- 13146aba-da50-4304-bbdf-eb05d5e1f8f9 (old id 1206367)
- date added to LUP
- 2016-04-01 13:41:01
- date last changed
- 2022-03-06 07:06:24
@article{13146aba-da50-4304-bbdf-eb05d5e1f8f9, abstract = {{Clostridium difficile PCR ribotype 027 comprised 0.2% of a collection of Swedish isolates in 1997-2001 (3 of 1,325 isolates). These isolates had lower moxifloxacin MICs than the epidemic type 027 isolates, but they had the same tcdC sequence and toxin yield. Type 027 produced 3- to 13-fold more toxin than did major Swedish types. One epidemic strain (027/NAP1a) sporulated more than did other type 027 isolates, a feature that should contribute to its survival and spread.}}, author = {{Åkerlund, Thomas and Persson, Ingela and Unemo, Magnus and Noren, Torbjörn and Svenungsson, Bo and Wullt, Marlene and Burman, Lars G}}, issn = {{1098-660X}}, language = {{eng}}, number = {{4}}, pages = {{1530--1533}}, publisher = {{American Society for Microbiology}}, series = {{Journal of Clinical Microbiology}}, title = {{Increased sporulation rate of epidemic clostridium difficile type 027/NAP1}}, url = {{http://dx.doi.org/10.1128/JCM.01964-07}}, doi = {{10.1128/JCM.01964-07}}, volume = {{46}}, year = {{2008}}, }