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Risk factors for depressive disorders in the Lundby cohort - A 50 year prospective clinical follow-up.

Mattisson, Cecilia LU ; Bogren, Mats LU ; Horstmann, Vibeke LU ; Tambs, Kristian; Munk-Jörgensen, Povl and Nettelbladt, Per LU (2009) In Journal of Affective Disorders 113(3). p.203-215
Abstract
BACKGROUND: Depressive disorders are common and disabling. The Lundby Study is a prospective study of a community sample that started in 1947(N=2550). In 1957, 1013 newcomers were added. The latest field investigation was carried out in 1997. AIM: To identify risk factors for depressive disorders. METHOD: The Lundby database contains clinical assessments of the subjects made by psychiatrists. It also includes information about socio-demographic factors and episodes of somatic and mental disorders. Two different but partly overlapping cohorts from the same geographical area in 1947 (N=2470) and in 1957 (N=3310) were investigated. During follow-up 418 individuals experienced their first depressive disorder. For each cohort, possible risk... (More)
BACKGROUND: Depressive disorders are common and disabling. The Lundby Study is a prospective study of a community sample that started in 1947(N=2550). In 1957, 1013 newcomers were added. The latest field investigation was carried out in 1997. AIM: To identify risk factors for depressive disorders. METHOD: The Lundby database contains clinical assessments of the subjects made by psychiatrists. It also includes information about socio-demographic factors and episodes of somatic and mental disorders. Two different but partly overlapping cohorts from the same geographical area in 1947 (N=2470) and in 1957 (N=3310) were investigated. During follow-up 418 individuals experienced their first depressive disorder. For each cohort, possible risk factors were analysed by means of Cox regression analyses for the whole sample and for each sex separately. CONCLUSION: The personality trait nervous/tense and anxiety disorders were statistically significant risk factors for depression for both genders. For males, the diagnoses alcohol disorders and tiredness disorder were risk factors. The personality trait subvalidity (low grade of energy) and nervous symptoms as a child were also risk factors for males. For females personality traits such as being easily hurt, abnormal/antisocial and tired/distracted were associated with depressive disorders. CLINICAL RELEVANCE: Knowledge of risk factors may help to reduce incidence of depression. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Affective Disorders
volume
113
issue
3
pages
203 - 215
publisher
Elsevier
external identifiers
  • wos:000263391100001
  • pmid:18694601
  • scopus:58749095680
ISSN
1573-2517
DOI
10.1016/j.jad.2008.07.002
language
English
LU publication?
yes
id
94e7e291-d9b5-4f71-ace8-4d7f164f454e (old id 1223278)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18694601?dopt=Abstract
date added to LUP
2008-09-02 13:46:02
date last changed
2017-01-01 07:40:55
@article{94e7e291-d9b5-4f71-ace8-4d7f164f454e,
  abstract     = {BACKGROUND: Depressive disorders are common and disabling. The Lundby Study is a prospective study of a community sample that started in 1947(N=2550). In 1957, 1013 newcomers were added. The latest field investigation was carried out in 1997. AIM: To identify risk factors for depressive disorders. METHOD: The Lundby database contains clinical assessments of the subjects made by psychiatrists. It also includes information about socio-demographic factors and episodes of somatic and mental disorders. Two different but partly overlapping cohorts from the same geographical area in 1947 (N=2470) and in 1957 (N=3310) were investigated. During follow-up 418 individuals experienced their first depressive disorder. For each cohort, possible risk factors were analysed by means of Cox regression analyses for the whole sample and for each sex separately. CONCLUSION: The personality trait nervous/tense and anxiety disorders were statistically significant risk factors for depression for both genders. For males, the diagnoses alcohol disorders and tiredness disorder were risk factors. The personality trait subvalidity (low grade of energy) and nervous symptoms as a child were also risk factors for males. For females personality traits such as being easily hurt, abnormal/antisocial and tired/distracted were associated with depressive disorders. CLINICAL RELEVANCE: Knowledge of risk factors may help to reduce incidence of depression.},
  author       = {Mattisson, Cecilia and Bogren, Mats and Horstmann, Vibeke and Tambs, Kristian and Munk-Jörgensen, Povl and Nettelbladt, Per},
  issn         = {1573-2517},
  language     = {eng},
  number       = {3},
  pages        = {203--215},
  publisher    = {Elsevier},
  series       = {Journal of Affective Disorders},
  title        = {Risk factors for depressive disorders in the Lundby cohort - A 50 year prospective clinical follow-up.},
  url          = {http://dx.doi.org/10.1016/j.jad.2008.07.002},
  volume       = {113},
  year         = {2009},
}