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Use of the harmonic scalpel versus conventional haemostatic techniques in patients with Grave disease undergoing total thyroidectomy: a prospective randomised controlled trial.

Hallgrimsson, Palli LU ; Lovén, L; Westerdahl, Johan LU and Bergenfelz, Anders LU (2008) In Langenbeck's Archives of Surgery 393. p.675-680
Abstract
INTRODUCTION: Thyrotoxicosis is often considered to be the most difficult thyroid operation because of the high vascularisation and the risk of bleeding. The conventional haemostatic technique in thyroidectomy today include knot tying and electrocoagulation. The introduction of the harmonic scalpel (HS) has led to further research if the use of the HS has any benefits in thyroid surgery. To our knowledge, no previous study has evaluated the HS dissection technique in a homogenous group of patients with Graves' disease undergoing total thyroidectomy. MATERIALS AND METHODS: Fifty-one patients (39 women and 12 men) with the pre-operative diagnosis of Graves' disease treated at two endocrine centers were randomised to total thyroidectomy with... (More)
INTRODUCTION: Thyrotoxicosis is often considered to be the most difficult thyroid operation because of the high vascularisation and the risk of bleeding. The conventional haemostatic technique in thyroidectomy today include knot tying and electrocoagulation. The introduction of the harmonic scalpel (HS) has led to further research if the use of the HS has any benefits in thyroid surgery. To our knowledge, no previous study has evaluated the HS dissection technique in a homogenous group of patients with Graves' disease undergoing total thyroidectomy. MATERIALS AND METHODS: Fifty-one patients (39 women and 12 men) with the pre-operative diagnosis of Graves' disease treated at two endocrine centers were randomised to total thyroidectomy with the use of the HS or with conventional haemostatic techniques. RESULTS: Twenty-seven patients were randomised to the harmonic group and 24 to the conventional group. The operating time was shorter in the HS group (median, 121 min; range, 84-213 min) compared to the conventional group (median, 172 min; range, 66-268 min; p = 0.011). CONCLUSION: The use of the HS was associated with a significant reduction in operating time compared to the use of the conventional haemostatic techniques in patients with Graves' disease undergoing total thyroidectomy. (Less)
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organization
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type
Contribution to journal
publication status
published
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in
Langenbeck's Archives of Surgery
volume
393
pages
675 - 680
publisher
Springer
external identifiers
  • WOS:000259007800010
  • PMID:18677509
  • Scopus:51449109359
ISSN
1435-2451
DOI
10.1007/s00423-008-0361-z
language
English
LU publication?
yes
id
b558c058-92c0-46b0-8a7d-838e1532795e (old id 1223527)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18677509?dopt=Abstract
date added to LUP
2008-09-10 11:43:29
date last changed
2017-01-01 07:50:10
@article{b558c058-92c0-46b0-8a7d-838e1532795e,
  abstract     = {INTRODUCTION: Thyrotoxicosis is often considered to be the most difficult thyroid operation because of the high vascularisation and the risk of bleeding. The conventional haemostatic technique in thyroidectomy today include knot tying and electrocoagulation. The introduction of the harmonic scalpel (HS) has led to further research if the use of the HS has any benefits in thyroid surgery. To our knowledge, no previous study has evaluated the HS dissection technique in a homogenous group of patients with Graves' disease undergoing total thyroidectomy. MATERIALS AND METHODS: Fifty-one patients (39 women and 12 men) with the pre-operative diagnosis of Graves' disease treated at two endocrine centers were randomised to total thyroidectomy with the use of the HS or with conventional haemostatic techniques. RESULTS: Twenty-seven patients were randomised to the harmonic group and 24 to the conventional group. The operating time was shorter in the HS group (median, 121 min; range, 84-213 min) compared to the conventional group (median, 172 min; range, 66-268 min; p = 0.011). CONCLUSION: The use of the HS was associated with a significant reduction in operating time compared to the use of the conventional haemostatic techniques in patients with Graves' disease undergoing total thyroidectomy.},
  author       = {Hallgrimsson, Palli and Lovén, L and Westerdahl, Johan and Bergenfelz, Anders},
  issn         = {1435-2451},
  language     = {eng},
  pages        = {675--680},
  publisher    = {Springer},
  series       = {Langenbeck's Archives of Surgery},
  title        = {Use of the harmonic scalpel versus conventional haemostatic techniques in patients with Grave disease undergoing total thyroidectomy: a prospective randomised controlled trial.},
  url          = {http://dx.doi.org/10.1007/s00423-008-0361-z},
  volume       = {393},
  year         = {2008},
}