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Epidemiology of extra-articular manifestations in rheumatoid arthritis.

Turesson, Carl LU and Jacobsson, L T H (2004) In Scandinavian Journal of Rheumatology 33(2). p.65-72
Abstract
Extra-articular RA (ExRA) includes a wide variety of disease manifestations. Although rheumatologists in general are aware that such events are clinically important, the heterogeneity of available data, including discrepancies in case definitions, has complicated constructive discussions on this aspect of the RA disease phenotype. In recent years, there has been a growing recognition of the importance of co-morbidity in patients with RA. ExRA manifestations are not uncommon, explain excess mortality in RA and are predicted by smoking and autoantibodies. Further studies of the mechanisms underlying these associations are likely to be important in improving our understanding of the systemic nature of RA. This article discusses the... (More)
Extra-articular RA (ExRA) includes a wide variety of disease manifestations. Although rheumatologists in general are aware that such events are clinically important, the heterogeneity of available data, including discrepancies in case definitions, has complicated constructive discussions on this aspect of the RA disease phenotype. In recent years, there has been a growing recognition of the importance of co-morbidity in patients with RA. ExRA manifestations are not uncommon, explain excess mortality in RA and are predicted by smoking and autoantibodies. Further studies of the mechanisms underlying these associations are likely to be important in improving our understanding of the systemic nature of RA. This article discusses the methodological issues involved in the study of ExRA manifestations, presents suggested criteria that have been used in clinical studies, and reviews important surveys of the epidemiology of extra-articular RA. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
rheumatoid arthritis, extra-articular manifestations, epidemiology, incidence, vasculitis, mortality, predictors
in
Scandinavian Journal of Rheumatology
volume
33
issue
2
pages
65 - 72
publisher
Taylor & Francis
external identifiers
  • wos:000220516400001
  • pmid:15163106
  • scopus:1842607230
ISSN
1502-7732
DOI
10.1080/03009740310004621
language
English
LU publication?
yes
id
84f51e2f-a0d7-4e5a-a85b-8ebfc840b3fc (old id 123298)
date added to LUP
2007-07-30 12:08:43
date last changed
2017-07-23 03:36:39
@article{84f51e2f-a0d7-4e5a-a85b-8ebfc840b3fc,
  abstract     = {Extra-articular RA (ExRA) includes a wide variety of disease manifestations. Although rheumatologists in general are aware that such events are clinically important, the heterogeneity of available data, including discrepancies in case definitions, has complicated constructive discussions on this aspect of the RA disease phenotype. In recent years, there has been a growing recognition of the importance of co-morbidity in patients with RA. ExRA manifestations are not uncommon, explain excess mortality in RA and are predicted by smoking and autoantibodies. Further studies of the mechanisms underlying these associations are likely to be important in improving our understanding of the systemic nature of RA. This article discusses the methodological issues involved in the study of ExRA manifestations, presents suggested criteria that have been used in clinical studies, and reviews important surveys of the epidemiology of extra-articular RA.},
  author       = {Turesson, Carl and Jacobsson, L T H},
  issn         = {1502-7732},
  keyword      = {rheumatoid arthritis,extra-articular manifestations,epidemiology,incidence,vasculitis,mortality,predictors},
  language     = {eng},
  number       = {2},
  pages        = {65--72},
  publisher    = {Taylor & Francis},
  series       = {Scandinavian Journal of Rheumatology},
  title        = {Epidemiology of extra-articular manifestations in rheumatoid arthritis.},
  url          = {http://dx.doi.org/10.1080/03009740310004621},
  volume       = {33},
  year         = {2004},
}